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Inheritance of two gene Questions in English

Class 12 Biology · Principles of Inheritance and Variation · Inheritance of two gene

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51
MediumMCQ
In rabbits,black skin $(B)$ is dominant over brown skin $(b)$ and short hair $(S)$ is dominant over long hair $(s)$. $A$ homozygous black,short-haired male is crossed with a homozygous brown,long-haired female. All $F_1$ offspring are heterozygous black,short-haired. If the $F_1$ male is crossed with an $F_1$ female,what is the percentage of homozygous black,short-haired offspring in the $F_2$ generation (in $\%$)?
A
$50$
B
$12.5$
C
$6.25$
D
$18.75$

Solution

(C) $1$. The parental genotypes are: Male (homozygous black,short-haired) = $BBSS$,Female (homozygous brown,long-haired) = $bbss$.
$2$. The $F_1$ generation offspring are all heterozygous for both traits: $BbSs$.
$3$. When $F_1$ individuals $(BbSs \times BbSs)$ are crossed,this is a dihybrid cross.
$4$. The phenotypic ratio of a dihybrid cross is $9:3:3:1$,but we need the genotypic frequency of homozygous black,short-haired offspring $(BBSS)$.
$5$. In a Punnett square of $BbSs \times BbSs$,the probability of obtaining $BBSS$ is calculated as: $P(BB) \times P(SS) = (1/4) \times (1/4) = 1/16$.
$6$. Converting $1/16$ to a percentage: $(1/16) \times 100 = 6.25\%$.
$7$. Therefore,the percentage of homozygous black,short-haired offspring in the $F_2$ generation is $6.25\%$.
52
MediumMCQ
$A$ heterozygous trihybrid plant produces .....
A
$8$ different gametes and $32$ different zygotes
B
$8$ different gametes and $64$ different zygotes
C
$4$ different gametes and $16$ different zygotes
D
$8$ different gametes and $16$ different zygotes

Solution

(B) For a plant that is heterozygous for $n$ genes (trihybrid means $n = 3$):
$1$. The number of different types of gametes produced is calculated by the formula $2^n$.
For a trihybrid $(n = 3)$,the number of gametes = $2^3 = 8$.
$2$. The number of different types of zygotes (genotypes) produced in an $F_2$ generation is calculated by the formula $3^n$.
For a trihybrid $(n = 3)$,the number of zygotes = $3^3 = 27$.
However,in the context of standard multiple-choice questions regarding Punnett square outcomes for trihybrids,the total number of combinations in the grid is $4^n = 4^3 = 64$.
Given the options,$8$ gametes and $64$ zygote combinations is the correct biological standard.
53
MediumMCQ
$A$ dihybrid plant produced by self-pollination yields $400$ seeds with $9$ different genotypes. How many seeds will have the $TtRr$ genotype?
A
$200$
B
$100$
C
$50$
D
$150$

Solution

(B) In a dihybrid cross involving self-pollination of a $TtRr$ plant,the phenotypic ratio is $9:3:3:1$ and the genotypic ratio is $1:2:1:2:4:2:1:2:1$.
Total number of seeds = $400$.
The genotype $TtRr$ represents the heterozygous condition for both traits.
According to the Mendelian dihybrid ratio,the probability of obtaining the $TtRr$ genotype is $4/16$ or $1/4$.
Therefore,the number of seeds with the $TtRr$ genotype = $(1/4) \times 400 = 100$.
54
MediumMCQ
In a dihybrid cross where two parents differ in their traits,such as yellow seeds $(YY)$ with round shape $(RR)$ and green seeds $(yy)$ with wrinkled shape $(rr)$,how many seeds out of the total $16$ in the $F_2$ generation will be green $(yy)$?
A
$2$
B
$4$
C
$6$
D
$8$

Solution

(B) In a dihybrid cross,the $F_2$ generation follows the phenotypic ratio of $9:3:3:1$.
Total number of offspring in $F_2$ generation = $16$.
The trait for seed color is yellow $(Y)$ dominant over green $(y)$.
According to the law of independent assortment,the phenotypic ratio for seed color alone is $3$ (yellow) : $1$ (green).
Out of $16$ total offspring,the number of green seeds $(yy)$ is calculated as: $(1/4) \times 16 = 4$.
Therefore,there will be $4$ green seeds in the $F_2$ generation.
55
MediumMCQ
In a cross between $TTRr$ and $ttrr$,what percentage of the offspring will be tall with red flowers (in $\%$)? (Assume $T$ is tall,$t$ is dwarf,$R$ is red,and $r$ is white).
A
$50$
B
$75$
C
$25$
D
$100$

Solution

(A) To find the percentage of offspring that are tall $(T-)$ and red $(R-)$,we perform a dihybrid cross between $TTRr$ and $ttrr$.
Step $1$: Determine the gametes produced by each parent.
Parent $1$ $(TTRr)$ produces gametes: $TR$ and $Tr$.
Parent $2$ $(ttrr)$ produces gametes: $tr$.
Step $2$: Perform the Punnett square cross.
- $TR \times tr = TtRr$ (Tall,Red)
- $Tr \times tr = Ttrr$ (Tall,White)
Step $3$: Analyze the results.
Out of the $2$ possible genotypes,$1$ is tall and red $(TtRr)$.
Therefore,the percentage of tall and red offspring is $(1/2) \times 100 = 50\%$.
56
MediumMCQ
In the $F_2$ generation of a dihybrid cross,how many types of genotypes are produced?
A
$1$
B
$4$
C
$9$
D
$16$

Solution

(C) In a dihybrid cross,the $F_2$ generation is produced by the selfing of $F_1$ dihybrids $(AaBb \times AaBb)$.
According to the law of independent assortment,the phenotypic ratio is $9:3:3:1$.
The number of genotypes can be calculated using the formula $3^n$,where $n$ is the number of gene pairs involved.
For a dihybrid cross,$n = 2$.
Therefore,the number of genotypes = $3^2 = 9$.
The $9$ genotypes are: $AABB, AABb, AaBB, AaBb, AAbb, Aabb, aaBB, aaBb, aabb$.
57
MediumMCQ
If the genotype of an organism for two pairs of genes is represented by $AaBb$,then the possible genetic combinations of gametes after meiosis will be:
A
$AB, Ab, aB, ab$
B
$AB, ab$
C
$Aa, Bb$
D
$A, a, B, b$

Solution

(A) According to the Law of Independent Assortment,during meiosis,the alleles of different genes segregate independently of each other.
For a genotype $AaBb$,the alleles $A$ and $a$ segregate,and $B$ and $b$ segregate.
Each gamete receives one allele from each gene pair.
Therefore,the possible combinations are formed by pairing each allele of the first gene ($A$ or $a$) with each allele of the second gene ($B$ or $b$).
The resulting combinations are $AB$,$Ab$,$aB$,and $ab$.
58
MediumMCQ
In a dihybrid cross between $AABB$ and $aabb$,the ratio of $AABB, AABb, aaBb,$ and $aabb$ in the $F_2$ generation is:
A
$9:3:3:1$
B
$1:1:1:1$
C
$1:2:2:1$
D
$1:1:2:2$

Solution

(C) In a dihybrid cross between $AABB$ and $aabb$,the $F_1$ generation produces $AaBb$ individuals.
When $F_1$ individuals $(AaBb)$ are self-crossed,the $F_2$ generation follows the Mendelian dihybrid ratio of $9:3:3:1$ (phenotypic).
However,the question asks for the specific genotypic ratio of the four given genotypes: $AABB, AABb, aaBb,$ and $aabb$.
In the $F_2$ Punnett square,the frequencies are:
$AABB = 1/16$
$AABb = 2/16$
$aaBb = 2/16$
$aabb = 1/16$
Thus,the ratio of $AABB : AABb : aaBb : aabb$ is $1:2:2:1$.
59
MediumMCQ
If a trihybrid cross is performed between two plants with the genotype $AaBbCc$,what proportion of the offspring will have the genotype $aabbcc$?
A
$1/64$
B
$1/4$
C
$1/16$
D
$1/32$

Solution

(A) In a trihybrid cross involving the genotype $AaBbCc \times AaBbCc$,the inheritance of each gene pair follows Mendel's Law of Independent Assortment.
We can calculate the probability of the genotype $aabbcc$ by considering each gene pair independently:
$1$. For the $Aa \times Aa$ cross,the probability of obtaining the $aa$ genotype is $1/4$.
$2$. For the $Bb \times Bb$ cross,the probability of obtaining the $bb$ genotype is $1/4$.
$3$. For the $Cc \times Cc$ cross,the probability of obtaining the $cc$ genotype is $1/4$.
Since these events are independent,the probability of the combined genotype $aabbcc$ is the product of the individual probabilities:
$P(aabbcc) = P(aa) \times P(bb) \times P(cc) = 1/4 \times 1/4 \times 1/4 = 1/64$.
60
MediumMCQ
How many pairs of chromosomes are involved in Mendelian dihybrid crosses and dihybrid crosses with linkage,respectively?
A
$2$ pairs and $1$ pair
B
$1$ pair and $2$ pairs
C
$2$ pairs and $2$ pairs
D
$1$ pair and $1$ pair

Solution

(A) In a Mendelian dihybrid cross,the two genes being studied are located on different pairs of homologous chromosomes,allowing for independent assortment. Therefore,it involves $2$ pairs of chromosomes.
In a dihybrid cross involving linkage,the two genes are located on the same pair of homologous chromosomes,meaning they are linked and do not assort independently. Therefore,it involves $1$ pair of chromosomes.
Thus,the correct sequence is $2$ pairs and $1$ pair.
61
DifficultMCQ
In plants,red color $(R)$ is dominant over yellow $(r)$ and tallness $(T)$ is dominant over dwarfness $(t)$. If a plant with genotype $RRTt$ is crossed with a plant with genotype $rrtt$,what will be the result?
A
All offspring will be red-fruited and tall.
B
$25\%$ will be red-fruited and tall.
C
$50\%$ will be red-fruited and tall.
D
$75\%$ will be red-fruited and tall.

Solution

(C) The cross is between $RRTt$ and $rrtt$.
$1$. Gametes produced by $RRTt$ are $RT$ and $Rt$.
$2$. Gametes produced by $rrtt$ are $rt$.
$3$. The resulting genotypes in the $F_1$ generation are:
- $RT \times rt = RrTt$ (Red,Tall)
- $Rt \times rt = Rrtt$ (Red,Dwarf)
$4$. The ratio of offspring is $1:1$ for Red-Tall and Red-Dwarf.
$5$. Thus,$50\%$ of the offspring will be red-fruited and tall,and $50\%$ will be red-fruited and dwarf.
62
EasyMCQ
The dihybrid cross is associated with the principle of . . . . . . .
A
Dominance
B
Segregation
C
Independent Assortment
D
Purity of Gametes

Solution

(C) The dihybrid cross involves the study of the inheritance of two pairs of contrasting traits simultaneously.
Gregor Mendel formulated the Law of Independent Assortment based on his observations from dihybrid cross experiments.
This law states that when two pairs of traits are combined in a hybrid,segregation of one pair of characters is independent of the other pair of characters.
Therefore,the dihybrid cross is associated with the principle of Independent Assortment.
63
MediumMCQ
Mendel's Law of Independent Assortment is proven by .....
A
Monohybrid cross
B
Test cross
C
Dihybrid cross
D
Reciprocal cross

Solution

(C) Mendel's Law of Independent Assortment states that when two pairs of traits are combined in a hybrid,segregation of one pair of characters is independent of the other pair of characters.
This law is based on the results of a dihybrid cross,where Mendel observed the inheritance of two different traits (e.g.,seed shape and seed color) simultaneously.
In a dihybrid cross,the phenotypic ratio obtained in the $F_2$ generation is $9:3:3:1$,which confirms that the alleles for different traits assort independently into the gametes.
64
DifficultMCQ
In a cross between $AABB$ and $aabb$,what is the probability of obtaining $AaBb$ in the $F_2$ generation (in $/16$)?
A
$1$
B
$2$
C
$8$
D
$4$

Solution

(D) In a dihybrid cross between $AABB$ and $aabb$,the $F_1$ generation produces $AaBb$ individuals.
When $F_1$ individuals $(AaBb)$ are self-crossed to produce the $F_2$ generation,the phenotypic ratio is $9:3:3:1$.
The genotypic ratio for the $F_2$ generation in a dihybrid cross is $1:2:1:2:4:2:1:2:1$.
Specifically,the genotype $AaBb$ is a double heterozygote.
In the Punnett square of a dihybrid cross,there are $16$ total combinations.
The genotype $AaBb$ appears $4$ times out of $16$.
Therefore,the probability of obtaining $AaBb$ is $4/16$ or $1/4$.
65
DifficultMCQ
In a plant,gene '$A$' is responsible for tallness and '$a$' is the recessive allele for dwarfness. Gene '$B$' is responsible for red flower color and '$b$' is the recessive allele for white flower color. $A$ plant with genotype $AaBb$ (tall and red) is crossed with a plant with genotype $aaBb$ (dwarf and red). What is the percentage of dwarf-white flowered plants in the progeny (in $\%$)?
A
$50$
B
$6.25$
C
$12.5$
D
$25$

Solution

(C) The cross is between $AaBb$ and $aaBb$.
We can analyze the inheritance of each gene independently:
$1$. For height: $Aa \times aa$ results in $Aa$ (tall) and $aa$ (dwarf) in a $1:1$ ratio. The probability of dwarf $(aa)$ is $1/2$.
$2$. For flower color: $Bb \times Bb$ results in $BB$ (red),$Bb$ (red),$Bb$ (red),and $bb$ (white) in a $3:1$ ratio. The probability of white $(bb)$ is $1/4$.
To find the probability of dwarf and white $(aabb)$,we multiply the individual probabilities:
$P(aa) \times P(bb) = 1/2 \times 1/4 = 1/8$.
Converting this to a percentage: $(1/8) \times 100 = 12.5\%$.
66
EasyMCQ
$A$ pure tall plant with green pods is crossed with a pure dwarf plant with yellow pods. How many dwarf plants will be produced out of $16$ in the $F_2$ generation?
A
$1$
B
$3$
C
$4$
D
$9$

Solution

(C) In a dihybrid cross between a pure tall green plant $(TTGG)$ and a pure dwarf yellow plant $(ttgg)$,the $F_1$ generation will be heterozygous tall and green $(TtGg)$.
When $F_1$ plants $(TtGg)$ are self-crossed,the $F_2$ generation follows the phenotypic ratio of $9:3:3:1$.
The total number of combinations in the $F_2$ generation is $16$.
The phenotypic categories are:
$9$ Tall and Green
$3$ Tall and Yellow
$3$ Dwarf and Green
$1$ Dwarf and Yellow
Since the question asks for the number of dwarf plants,we must consider both 'Dwarf and Green' $(3)$ and 'Dwarf and Yellow' $(1)$.
Total dwarf plants = $3 + 1 = 4$.
67
MediumMCQ
How many types of gametes are produced by a dihybrid plant?
A
One
B
Two
C
Four
D
Eight

Solution

(C) dihybrid plant is heterozygous for two traits,represented by the genotype $AaBb$.
According to the law of independent assortment,the alleles of different genes segregate independently during gamete formation.
The number of types of gametes produced by an organism can be calculated using the formula $2^n$,where $n$ is the number of heterozygous gene pairs.
For a dihybrid plant,$n = 2$ (since there are two heterozygous pairs,$Aa$ and $Bb$).
Therefore,the number of types of gametes = $2^2 = 4$.
The four types of gametes produced are $AB, Ab, aB,$ and $ab$.
68
DifficultMCQ
$A$ human male is heterozygous for autosomal genes $A$ and $B$ and is also hemophilic (gene $h$). What proportion of his sperm will contain the $abh$ gene combination?
A
$1/4$
B
$1/8$
C
$1/32$
D
$1/16$

Solution

(B) The genotype of the male is $AaBbX^hY$.
Since the genes $A$ and $B$ are autosomal and heterozygous,and the hemophilia gene $h$ is $X$-linked,we determine the gamete formation using the principle of independent assortment.
The possible gametes for the autosomal genes $AaBb$ are $AB, Ab, aB,$ and $ab$. Each occurs with a probability of $1/4$.
The sex chromosomes are $X^h$ and $Y$. Each occurs with a probability of $1/2$.
To get the combination $abh$,the sperm must carry the autosomal combination $ab$ and the $X^h$ chromosome.
The probability of $ab$ is $1/4$.
The probability of $X^h$ is $1/2$.
Therefore,the probability of the sperm being $abh$ is $(1/4) \times (1/2) = 1/8$.
69
EasyMCQ
If the cross is $Aabb \times aaBb$,what will be the genotypic ratio of the offspring?
A
$9:3:3:1$
B
$1:2:1$
C
$1:1:1:1$
D
$4:1$

Solution

(C) To find the genotypic ratio of the cross $Aabb \times aaBb$,we can treat the two genes independently as they assort independently.
Step $1$: Analyze the first gene cross: $Aa \times aa$. The offspring genotypes are $Aa$ and $aa$ in a ratio of $1:1$.
Step $2$: Analyze the second gene cross: $bb \times Bb$. The offspring genotypes are $Bb$ and $bb$ in a ratio of $1:1$.
Step $3$: Combine the results using the product rule: $(Aa + aa) \times (Bb + bb) = AaBb + Aabb + aaBb + aabb$.
This results in four genotypes: $AaBb$,$Aabb$,$aaBb$,and $aabb$,each appearing with a frequency of $1/4$. Therefore,the genotypic ratio is $1:1:1:1$.
70
DifficultMCQ
In a plant with genotype $RrYy$,if self-pollination occurs,what will be the ratio of the following genotypes: $RRYY, RrYY, RRYy, RrYy$?
A
$1:2:2:4$
B
$1:2:2:1$
C
$1:1:1:1$
D
$2:2:2:1$

Solution

(A) In a dihybrid cross involving $RrYy \times RrYy$,the Punnett square yields $16$ combinations.
The genotypes and their frequencies are as follows:
$RRYY: 1$
$RRYy: 2$
$RrYY: 2$
$RrYy: 4$
$RRyy: 1$
$Rryy: 2$
$rrYY: 1$
$rryy: 1$
$rrYy: 2$
Given the specific genotypes requested: $RRYY (1), RrYY (2), RRYy (2), RrYy (4)$.
Thus,the ratio is $1:2:2:4$.
71
MediumMCQ
The law of dihybrid cross proves which of the following?
A
Segregation
B
Purity of gametes
C
Dominance
D
Law of independent assortment

Solution

(D) The dihybrid cross involves the inheritance of two pairs of contrasting traits simultaneously.
Gregor Mendel observed that the inheritance of one pair of traits is independent of the inheritance of the other pair.
This observation led to the formulation of the $Law$ $of$ $Independent$ $Assortment$.
Therefore,the dihybrid cross is the experimental basis that proves the $Law$ $of$ $Independent$ $Assortment$.
72
DifficultMCQ
When $AABbcc$ is crossed with $AaBbCc$,what is the probability of obtaining an offspring with the genotype $AaBbcc$?
A
$1/8$
B
$1/4$
C
$1/16$
D
$1/32$

Solution

(A) To find the probability of the genotype $AaBbcc$ from the cross $AABbcc \times AaBbCc$,we analyze each gene locus independently:
$1$. For gene $A$: The cross is $AA \times Aa$. The offspring genotypes are $AA$ and $Aa$ in a $1:1$ ratio. The probability of $Aa$ is $1/2$.
$2$. For gene $B$: The cross is $Bb \times Bb$. The offspring genotypes are $BB$,$Bb$,$Bb$,and $bb$ in a $1:2:1$ ratio. The probability of $Bb$ is $2/4 = 1/2$.
$3$. For gene $C$: The cross is $cc \times Cc$. The offspring genotypes are $Cc$ and $cc$ in a $1:1$ ratio. The probability of $cc$ is $1/2$.
Since these genes assort independently,the probability of the combined genotype $AaBbcc$ is the product of the individual probabilities: $P(Aa) \times P(Bb) \times P(cc) = 1/2 \times 1/2 \times 1/2 = 1/8$.
73
MediumMCQ
$A$ trihybrid cross involves three pairs of traits,which gives an $F_1$ hybrid that is heterozygous for three genes. How many types of gametes will be produced in both male and female?
A
$2$
B
$4$
C
$6$
D
$8$

Solution

(D) The number of different types of gametes produced by an organism can be calculated using the formula $2^n$,where $n$ represents the number of heterozygous gene pairs.
In a trihybrid cross,the $F_1$ hybrid is heterozygous for three genes,so $n = 3$.
Therefore,the number of types of gametes produced is $2^3 = 2 \times 2 \times 2 = 8$.
Both the male and female parents produce $8$ types of gametes.
74
EasyMCQ
When a dihybrid plant with dominant traits of red color and tall height $(RrTt)$ is crossed with a recessive plant having white color and dwarf height $(rrtt)$,what will be the phenotypic ratio of the offspring for red-tall,red-dwarf,white-tall,and white-dwarf respectively?
A
$1:1:1:1$
B
$9:3:3:1$
C
$3:1:3:1$
D
$1:2:1:2$

Solution

(A) This is a classic test cross involving two genes. The genotype of the dihybrid parent is $RrTt$,which produces four types of gametes: $RT, Rt, rT, rt$. The recessive parent is $rrtt$,which produces only one type of gamete: $rt$.
By performing a Punnett square cross between $(RT, Rt, rT, rt)$ and $(rt)$,the resulting offspring genotypes are $RrTt$ (red-tall),$Rrtt$ (red-dwarf),$rrTt$ (white-tall),and $rrtt$ (white-dwarf).
Since each genotype appears with equal frequency,the phenotypic ratio is $1:1:1:1$.
75
MediumMCQ
What should be the phenotypic ratio of a test cross between a trihybrid and a homozygous recessive parent?
A
$1:1$
B
$1:1:1:1$
C
$1:1:1:1:1:1$
D
$1:1:1:1:1:1:1:1$

Solution

(D) test cross is performed to determine the genotype of an organism by crossing it with a homozygous recessive parent.
For a trihybrid organism (genotype $AaBbCc$),the gametes produced are $ABC, ABc, AbC, Abc, aBC, aBc, abC, abc$ (total $8$ types).
The homozygous recessive parent (genotype $aabbcc$) produces only one type of gamete: $abc$.
When these are crossed,the resulting offspring will have $8$ different genotypes and phenotypes in a ratio of $1:1:1:1:1:1:1:1$ ($2^3 = 8$ combinations).
Therefore,the phenotypic ratio is $1:1:1:1:1:1:1:1$.
76
DifficultMCQ
In the cross $AABb \times aaBb$,the ratio of progeny $AaBB : AaBb : Aabb : aabb$ is:
A
$0:3:1:1$
B
$1:2:1:0$
C
$1:1:1:1$
D
$1:2:1:1$

Solution

(B) To find the ratio of the progeny for the cross $AABb \times aaBb$,we can analyze the inheritance of each gene pair independently (Mendel's Law of Independent Assortment).
$1$. For the first gene pair $(AA \times aa)$: All offspring will be $Aa$. Thus,the ratio is $1$ $Aa$.
$2$. For the second gene pair $(Bb \times Bb)$: This is a monohybrid cross resulting in a genotypic ratio of $1 BB : 2 Bb : 1 bb$.
$3$. Combining these results:
- $AaBB = 1 \times 1 = 1$
- $AaBb = 1 \times 2 = 2$
- $Aabb = 1 \times 1 = 1$
- $aabb = 1 \times 0 = 0$
Therefore,the ratio of $AaBB : AaBb : Aabb : aabb$ is $1:2:1:0$.
77
DifficultMCQ
How many types of gametes are produced in the $F_1$ generation of a trihybrid cross?
A
$3$
B
$4$
C
$8$
D
$16$

Solution

(C) In a trihybrid cross,the organism is heterozygous for three different genes (e.g.,$AaBbCc$).
To determine the number of types of gametes produced by an organism,we use the formula $2^n$,where $n$ is the number of heterozygous gene pairs.
For a trihybrid cross,$n = 3$.
Therefore,the number of types of gametes = $2^3 = 2 \times 2 \times 2 = 8$.
The gametes produced would be $ABC, ABc, AbC, Abc, aBC, aBc, abC, abc$.
78
MediumMCQ
$A$ human male produces sperms with the genotypes $AB, Ab, aB,$ and $ab$ pertaining to two diallelic characters in equal proportions. What is the corresponding genotype of this person?
A
$AaBB$
B
$AABb$
C
$AABB$
D
$AaBb$

Solution

(D) The production of four types of gametes $(AB, Ab, aB, ab)$ in equal proportions indicates that the individual is heterozygous for both genes.
According to the law of independent assortment,a dihybrid individual with the genotype $AaBb$ produces four types of gametes in equal frequency $(1:1:1:1)$.
Therefore,the genotype of the person must be $AaBb$.
79
MediumMCQ
In Mendel's experiments with garden pea,round seed shape $(RR)$ was dominant over wrinkled seeds $(rr)$,and yellow cotyledon $(YY)$ was dominant over green cotyledon $(yy)$. What are the expected phenotypes of the $F_1$ generation when a homozygous round yellow plant $(RRYY)$ is crosseded with a homozygous wrinkled green plant $(rryy)$?
A
Round seeds with yellow cotyledons
B
Only round seeds with green cotyledons
C
Only wrinkled seeds with yellow cotyledons
D
Only wrinkled seeds with green cotyledons

Solution

(A) In a dihybrid cross between a homozygous round yellow plant $(RRYY)$ and a homozygous wrinkled green plant $(rryy)$,the gametes produced by the parents are $RY$ and $ry$ respectively.
When these gametes fuse,the resulting $F_1$ generation genotype is $RrYy$.
Since round $(R)$ is dominant over wrinkled $(r)$ and yellow $(Y)$ is dominant over green $(y)$,the phenotype of the $F_1$ generation will be round seeds with yellow cotyledons.
80
MediumMCQ
In a dihybrid cross between $RRYY$ and $rryy$,the number of $RrYy$ $F_2$ genotypes will be
A
$4$
B
$3$
C
$2$
D
$9$

Solution

(A) In a dihybrid cross,the $F_1$ generation obtained from crossing $RRYY$ and $rryy$ is $RrYy$.
When $F_1$ individuals $(RrYy)$ are self-crossed to produce the $F_2$ generation,the phenotypic ratio is $9:3:3:1$.
The genotypic ratio in the $F_2$ generation of a dihybrid cross is $1:2:1:2:4:2:1:2:1$.
Specifically,the genotype $RrYy$ is a double heterozygote.
In the Punnett square of a dihybrid cross,the frequency of the $RrYy$ genotype is $4$ out of $16$ total combinations.
Therefore,the number of $RrYy$ genotypes in the $F_2$ generation is $4$.
81
MediumMCQ
In an experiment on pea plant,pure plants with yellow round seeds $(YYRR)$ were crossed with plants producing green wrinkled seeds $(yyrr)$. What will be the phenotypic ratio of $F_1$ progeny?
A
$9$ yellow round : $3$ round green : $3$ wrinkled yellow : $1$ green wrinkled
B
All wrinkled green
C
$1$ round yellow : $1$ round green : $1$ wrinkled yellow : $1$ wrinkled green
D
All yellow round

Solution

(D) According to Mendel's Law of Dominance,when a cross is made between two pure-breeding parents for two contrasting traits (dihybrid cross),the $F_1$ generation expresses only the dominant traits.
In this case,yellow color $(Y)$ is dominant over green $(y)$,and round shape $(R)$ is dominant over wrinkled $(r)$.
The cross is $YYRR \times yyrr$.
The gametes produced by $YYRR$ are $YR$,and those by $yyrr$ are $yr$.
Upon fertilization,the $F_1$ progeny will have the genotype $YyRr$.
Since $Y$ and $R$ are dominant,all $F_1$ individuals will exhibit the yellow round phenotype.
82
MediumMCQ
Mendel's law of independent assortment is based on the $F_2$ ratio of:
A
$1:2:1$
B
$9:3:3:1$
C
$2:1$
D
$3:1$

Solution

(B) Mendel's law of independent assortment states that when two pairs of traits are combined in a hybrid,segregation of one pair of characters is independent of the other pair of characters.
This law is demonstrated by a dihybrid cross,where two contrasting traits are considered simultaneously.
In a dihybrid cross (e.g.,crossing round-yellow seeds with wrinkled-green seeds),the $F_2$ generation exhibits four different phenotypes in the ratio of $9:3:3:1$.
This specific phenotypic ratio confirms that the genes for different traits assort independently during gamete formation.
83
MediumMCQ
Which of the following gametes are produced by an individual with genotype $RrYy$?
A
$Ry, RY$
B
$ry, ry$
C
$Ry, ry, rY$
D
$Ry, RY, rY, ry$

Solution

(D) According to the Law of Independent Assortment,the alleles of two different genes segregate independently during gamete formation.
For a genotype $RrYy$,the possible combinations of alleles in the gametes are determined by the segregation of $R/r$ and $Y/y$.
Each gamete will receive one allele for each gene.
The possible combinations are:
$1$. $R$ with $Y = RY$
$2$. $R$ with $y = Ry$
$3$. $r$ with $Y = rY$
$4$. $r$ with $y = ry$
Therefore,the four types of gametes produced are $RY, Ry, rY,$ and $ry$.
84
MediumMCQ
$A$ dihybrid condition is represented by:
A
$tt\, Rr$
B
$Tt\, rr$
C
$tt\, rr$
D
$Tt\, Rr$

Solution

(D) dihybrid condition refers to an organism that is heterozygous for two different traits or genes.
In the given options,$Tt\, Rr$ represents an individual that is heterozygous for both the gene controlling height $(T/t)$ and the gene controlling seed shape $(R/r)$.
Therefore,$Tt\, Rr$ is the correct representation of a dihybrid genotype.
85
MediumMCQ
In a dihybrid cross between a pure tall pea plant with green pods and a dwarf pea plant with yellow pods,how many dwarf plants with yellow pods will be produced in the $F_2$ generation out of $16$ offspring?
A
$9$
B
$3$
C
$4$
D
$1$

Solution

(D) Let $T$ be the allele for tallness and $t$ for dwarfness. Let $G$ be the allele for green pods and $g$ for yellow pods.
The cross is between a pure tall green plant $(TTGG)$ and a dwarf yellow plant $(ttgg)$.
The $F_1$ generation will be $TtGg$ (tall and green).
In the $F_2$ generation,the phenotypic ratio for a dihybrid cross is $9:3:3:1$.
The distribution is as follows:
- Tall and Green: $9$
- Tall and Yellow: $3$
- Dwarf and Green: $3$
- Dwarf and Yellow: $1$
Therefore,out of $16$ offspring,only $1$ plant will be dwarf with yellow pods $(ttgg)$.
86
MediumMCQ
In a dihybrid cross between $AABB$ and $aabb$,the $F_2$ generation produces offspring with genotypes $AABB$,$AABb$,$AaBB$,and $AaBb$. What will be their phenotypic ratio?
A
$1 : 1 : 1 : 1$
B
$9 : 3 : 3 : 1$
C
$1 : 2 : 2 : 1$
D
$1 : 2 : 2 : 4$

Solution

(B) In a dihybrid cross,the $F_1$ generation produces $AaBb$ individuals. When $AaBb$ is self-crossed to produce the $F_2$ generation,the phenotypic ratio follows Mendel's Law of Independent Assortment.
For a dihybrid cross involving two traits,the phenotypic ratio of the $F_2$ generation is $9 : 3 : 3 : 1$.
This ratio represents the four possible phenotypes: both dominant,one dominant and one recessive,one recessive and one dominant,and both recessive.
87
DifficultMCQ
In plants,red fruit $(R)$ is dominant over yellow fruit $(r)$ and tall height $(T)$ is dominant over dwarf height $(t)$. If a plant with genotype $RRTt$ is crossed with a plant with genotype $RRTt$,what will be the phenotype of the offspring?
A
$75\%$ will be tall and red-fruited.
B
$50\%$ will be tall and red-fruited.
C
$25\%$ will be tall and red-fruited.
D
All offspring will be tall and red-fruited.

Solution

(A) The cross is between $RRTt \times RRTt$.
$1$. For the fruit color gene $(RR \times RR)$,all offspring will be $RR$ (red-fruited).
$2$. For the height gene $(Tt \times Tt)$,the offspring genotypes will be $1 TT : 2 Tt : 1 tt$.
$3$. Phenotypically,$3/4$ $(75\%)$ will be tall ($TT$ and $Tt$) and $1/4$ $(25\%)$ will be dwarf $(tt)$.
$4$. Combining these,all offspring will have red fruit,and $75\%$ will be tall.
Therefore,$75\%$ of the offspring will be tall and red-fruited.
88
MediumMCQ
To determine the different types of gametes produced by a pea plant with the genotype $AaBb$,with which genotype should it be crossed?
A
$aaBB$
B
$AaBb$
C
$AABB$
D
$aabb$

Solution

(D) To determine the genotype of an individual or the types of gametes produced,a test cross is performed.
In a test cross,the individual with an unknown genotype or the one whose gamete production is being analyzed is crossed with a homozygous recessive individual.
For the genotype $AaBb$,the homozygous recessive genotype is $aabb$.
By crossing $AaBb$ with $aabb$,the resulting offspring will reflect the types of gametes produced by the $AaBb$ parent,as the $aabb$ parent only contributes $ab$ gametes.
89
MediumMCQ
In Mendel's pea plants,round seeds $(RR)$ are dominant over wrinkled seeds $(rr)$,and yellow cotyledons $(YY)$ are dominant over green cotyledons $(yy)$. What will be the phenotypic ratio in the $F_2$ generation of a cross between $RRYY$ and $rryy$?
A
Only round seeds and green cotyledons
B
Only wrinkled seeds and yellow cotyledons
C
Only wrinkled seeds and green cotyledons
D
Round seeds and yellow cotyledons,and wrinkled seeds and green cotyledons

Solution

(D) $1$. The cross between $RRYY$ (round,yellow) and $rryy$ (wrinkled,green) is a dihybrid cross.
$2$. The $F_1$ generation will be $RrYy$ (round,yellow).
$3$. In the $F_2$ generation,selfing of $F_1$ $(RrYy \times RrYy)$ results in four phenotypes in the ratio $9:3:3:1$.
$4$. The four phenotypes are: Round-Yellow $(9)$,Round-Green $(3)$,Wrinkled-Yellow $(3)$,and Wrinkled-Green $(1)$.
$5$. The question asks for the phenotypic expression in the $F_2$ generation. The possible phenotypes are Round-Yellow,Round-Green,Wrinkled-Yellow,and Wrinkled-Green.
90
MediumMCQ
$A$ human male produces four types of gametes $AB, Ab, aB,$ and $ab$ in equal proportions. What is the corresponding genotype of this individual?
A
$AaBb$
B
$AaBB$
C
$AABb$
D
$AABB$

Solution

(A) According to the law of independent assortment,an individual produces different types of gametes based on their genotype.
For an individual to produce four types of gametes $(AB, Ab, aB, ab)$ in equal proportions,the individual must be heterozygous for both gene pairs.
The genotype $AaBb$ undergoes meiosis to produce gametes through independent assortment.
The possible combinations are $AB, Ab, aB,$ and $ab$,each occurring with a probability of $25\%$ or $1/4$.
Therefore,the correct genotype is $AaBb$.
91
EasyMCQ
$A$ diploid organism is heterozygous for $4$ loci. How many types of gametes can be produced?
A
$8$
B
$16$
C
$32$
D
$64$

Solution

(B) The number of different types of gametes produced by an organism heterozygous for $n$ loci (assuming independent assortment) is given by the formula $2^n$.
Here,the organism is heterozygous for $4$ loci,so $n = 4$.
Therefore,the number of types of gametes produced is $2^4 = 2 \times 2 \times 2 \times 2 = 16$.
If the genes are linked,the number of gamete types will be less than $16$ because linked genes are inherited together during meiosis.
Solution diagram
92
Difficult
When a cross is made between a tall plant with yellow seeds $(TtYy)$ and a tall plant with green seeds $(Ttyy)$,what proportions of phenotypes in the offspring could be expected to be:
$(a)$ Tall and green.
$(b)$ Dwarf and green.

Solution

(N/A) To determine the phenotypic ratio,we perform a Punnett square cross between the parents $TtYy$ and $Ttyy$.
$1$. Gametes produced by $TtYy$: $TY, Ty, tY, ty$.
$2$. Gametes produced by $Ttyy$: $Ty, ty$.
By crossing these gametes in a Punnett square:
| | $Ty$ | $ty$ |
|---|---|---|
| $TY$ | $TtYy$ (Tall,Yellow) | $TtYy$ (Tall,Yellow) |
| $Ty$ | $TTyy$ (Tall,Green) | $Ttyy$ (Tall,Green) |
| $tY$ | $TtYy$ (Tall,Yellow) | $ttYy$ (Dwarf,Yellow) |
| $ty$ | $Ttyy$ (Tall,Green) | $ttyy$ (Dwarf,Green) |
From the resulting $8$ offspring:
$(a)$ Tall and green plants: $3$ $(TTyy, Ttyy, Ttyy)$. Proportion = $3/8$.
$(b)$ Dwarf and green plants: $1$ $(ttyy)$. Proportion = $1/8$.
Solution diagram
93
Medium
Describe Mendel's experiment on pea plants involving two different traits.

Solution

(N/A) cross between two plants that differ in two traits is called a dihybrid cross.
Mendel conducted experiments to study the inheritance of two traits simultaneously in pea plants. For example,he chose plants with yellow,round seeds and green,wrinkled seeds as parents.
The yellow color is dominant over the green color,and the round shape is dominant over the wrinkled shape.
Genetic symbols: $Y$ - dominant (yellow),$y$ - recessive (green); similarly,$R$ - round shape (dominant),$r$ - wrinkled shape (recessive). The genotype of the parents can be represented as $YYRR \times yyrr$.
In the $F_1$ generation,all plants are heterozygous $(RrYy)$ and show the dominant phenotype (round yellow). Upon self-pollination of $F_1$ plants,the $F_2$ generation is produced,which shows a phenotypic ratio of $9:3:3:1$.
Solution diagram
94
Medium
Explain the Law of Independent Assortment based on a dihybrid cross.

Solution

(N/A) The Law of Independent Assortment states that when two pairs of traits are combined in a hybrid,segregation of one pair of characters is independent of the other pair of characters.
In a dihybrid cross,the phenotypic ratio of round-yellow,round-green,wrinkled-yellow,and wrinkled-green seeds was observed as $9:3:3:1$. This ratio can be derived as a combination of $3$ yellow : $1$ green and $3$ round : $1$ wrinkled.
This can be expressed as: $(3 \text{ Round} : 1 \text{ Wrinkled}) \times (3 \text{ Yellow} : 1 \text{ Green}) = 9 \text{ Round-Yellow} : 3 \text{ Round-Green} : 3 \text{ Wrinkled-Yellow} : 1 \text{ Wrinkled-Green}$.
Based on the results of the dihybrid cross,Mendel proposed the Law of Independent Assortment.
In the $F_1$ generation $(RrYy)$,the independent segregation of two pairs of genes can be understood using a Punnett square.
During gamete formation,$50\%$ of the gametes carry the $R$ allele and $50\%$ carry the $r$ allele. Similarly,$50\%$ of the gametes carry the $Y$ allele and $50\%$ carry the $y$ allele. Because segregation is independent,four types of gametes are produced in equal proportions: $RY, Ry, rY, ry$ (each with a probability of $1/4$).
By placing these gametes on the axes of a Punnett square,we obtain $16$ combinations in the $F_2$ generation.
The phenotypic ratio is $9:3:3:1$ (Round-Yellow : Round-Green : Wrinkled-Yellow : Wrinkled-Green).
The genotypic ratio is $1:2:2:4:1:2:1:2:1$.
95
Medium
$A, B, D$ are three independently assorting genes with their recessive alleles $a, b, d$,respectively. $A$ cross was made between individuals of $Aa bb DD$ genotype with $aa bb dd$. Find out the types of genotypes of the offspring produced.

Solution

(A) The given cross is $Aa bb DD \times aa bb dd$.
Since the genes assort independently,we can analyze the inheritance of each gene separately:
$1$. For gene $A$: $Aa \times aa$ produces $Aa$ and $aa$ in a $1:1$ ratio.
$2$. For gene $B$: $bb \times bb$ produces only $bb$ (all offspring).
$3$. For gene $D$: $DD \times dd$ produces only $Dd$ (all offspring).
Combining these results,the possible genotypes of the offspring are:
- $(Aa) \times (bb) \times (Dd) = Aa bb Dd$
- $(aa) \times (bb) \times (Dd) = aa bb Dd$
Thus,the offspring produced will have two genotypes: $Aa bb Dd$ and $aa bb Dd$ in a $1:1$ ratio.
96
Medium
In peas,tallness is dominant over dwarfness and red colour of flowers is dominant over the white colour. When a tall plant bearing red flowers was pollinated with a dwarf plant bearing white flowers,the different phenotypic groups were obtained in the progeny in numbers mentioned against them:
Tall,Red $= 138$
Tall,White $= 132$
Dwarf,Red $= 136$
Dwarf,White $= 128$
Mention the genotypes of the two parents and of the four offspring types.

Solution

(A) The result shows that the four types of offspring are in a ratio of $1:1:1:1$. Such a result is observed in a test-cross progeny of a dihybrid cross. The cross can be represented as:
Parents: Tall and Red $(TtRr)$ $\times$ Dwarf and White $(ttrr)$
The gametes produced by the tall red parent $(TtRr)$ are $TR, Tr, tR, tr$,while the dwarf white parent $(ttrr)$ produces only $tr$ gametes.
The resulting offspring genotypes are:
$1. TtRr$ (Tall,Red)
$2. Ttrr$ (Tall,White)
$3. ttRr$ (Dwarf,Red)
$4. ttrr$ (Dwarf,White)
Thus,the genotypes of the parents are $TtRr$ and $ttrr$,and the genotypes of the four offspring types are $TtRr, Ttrr, ttRr,$ and $ttrr$.
97
Medium
In a plant, tallness is dominant over dwarfness and red flower is dominant over white. Starting with the parents, work out a dihybrid cross. What is the standard dihybrid ratio? Do you think the values would deviate if the two genes in question are interacting with each other?

Solution

(D) The parents are $TTRR$ (Tall Red) and $ttrr$ (Dwarf White).
$F_{1}$ generation: $TtRr$ (Tall Red) $\times$ $TtRr$ (Selfing).
$F_{2}$ generation Punnett Square:
Gametes$TR$$Tr$$tR$$tr$
$TR$$TTRR$ (Tall Red)$TTRr$ (Tall Red)$TtRR$ (Tall Red)$TtRr$ (Tall Red)
$Tr$$TTRr$ (Tall Red)$Ttrr$ (Tall White)$TtRr$ (Tall Red)$Ttrr$ (Tall White)
$tR$$TtRR$ (Tall Red)$TtRr$ (Tall Red)$ttRR$ (Dwarf Red)$ttRr$ (Dwarf Red)
$tr$$TtRr$ (Tall Red)$Ttrr$ (Tall White)$ttRr$ (Dwarf Red)$ttrr$ (Dwarf White)

The standard dihybrid phenotypic ratio is $9:3:3:1$.
Yes, the values would deviate if the two genes interact with each other (e.g., epistasis or complementary gene action), as the independent assortment of traits would be altered.
98
Medium
Describe the inheritance of two genes.

Solution

(N/A) Mendel studied the inheritance of two genes by crossing pea plants that differed in two traits,such as seed color (yellow vs. green) and seed shape (round vs. wrinkled).
He crossed a plant with yellow,round seeds $(RRYY)$ with a plant having green,wrinkled seeds $(rryy)$.
The $F_{1}$ generation plants were all yellow and round $(RrYy)$,indicating that yellow color is dominant over green and round shape is dominant over wrinkled.
When Mendel self-pollinated the $F_{1}$ plants,the $F_{2}$ generation showed four types of phenotypes in a $9:3:3:1$ ratio: yellow-round,yellow-wrinkled,green-round,and green-wrinkled.
This experiment demonstrated the Law of Independent Assortment,which states that the segregation of one pair of traits is independent of the other pair of traits during gamete formation.
99
Medium
State the Law of Independent Assortment and explain how it is derived.

Solution

(A) The Law of Independent Assortment states that when two pairs of traits are combined in a hybrid,the segregation of one pair of characters is independent of the other pair of characters during gamete formation.
These characters are randomly rearranged in the offspring,producing both parental and new combinations of traits.
In a dihybrid cross,the phenotypes (round yellow,wrinkled yellow,round green,and wrinkled green) appeared in a ratio of $9:3:3:1$.
This ratio was observed for several pairs of characters studied by Mendel.
The ratio of $9:3:3:1$ can be derived as a combination of the monohybrid ratios: $(3 \text{ round} : 1 \text{ wrinkled}) \times (3 \text{ yellow} : 1 \text{ green}) = 9 \text{ round yellow} : 3 \text{ wrinkled yellow} : 3 \text{ round green} : 1 \text{ wrinkled green}$.
Based on these observations of dihybrid crosses,Mendel proposed the Law of Independent Assortment.
The Punnett Square is used to understand the independent segregation of two pairs of genes during meiosis in an $F_1$ $RrYy$ plant.
During segregation,$50\%$ of the gametes receive the gene $R$ and $50\%$ receive $r$. Similarly,$50\%$ receive $Y$ and $50\%$ receive $y$.
Since the segregation of the $R/r$ pair is independent of the $Y/y$ pair,each gamete has a $25\%$ $(1/4)$ probability of being $RY$,$Ry$,$rY$,or $ry$.
By placing these four types of gametes on the axes of a Punnett Square,one can easily derive the genotypes of the $F_2$ generation.
100
Easy
Define/Explain: Dihybrid cross.

Solution

(N/A) dihybrid cross is a genetic cross between two individuals that are heterozygous for two different traits. It involves the study of the inheritance patterns of two pairs of contrasting characters simultaneously. For example,crossing a plant with round and yellow seeds $(RRYY)$ with a plant having wrinkled and green seeds $(rryy)$.

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