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Multiple alleles Questions in English

Class 12 Biology · Principles of Inheritance and Variation · Multiple alleles

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51
MediumMCQ
Identify the incorrect statement regarding the gene '$I$' that controls the $ABO$ blood grouping.
A
The gene '$I$' has three alleles.
B
$A$ person possesses only two of the three alleles.
C
When $I^A$ and $I^B$ are present together,they express the same type of sugar.
D
The allele '$i$' does not produce any type of sugar.

Solution

(C) The gene '$I$' controls the $ABO$ blood grouping and exists in three allelic forms: $I^A$,$I^B$,and $i$.
Since humans are diploid organisms,each individual possesses only two of these three alleles.
The alleles $I^A$ and $I^B$ produce different types of sugar polymers on the surface of red blood cells,whereas the allele '$i$' does not produce any sugar.
Therefore,the statement that $I^A$ and $I^B$ express the same type of sugar is incorrect,as they are codominant and produce different sugars.
52
Easy
Define/Explain: Multiple Allelism.

Solution

(N/A) Multiple allelism refers to the presence of more than two alleles for a single gene locus within a population. Although a single diploid individual can only carry a maximum of two alleles at a specific locus,the population as a whole exhibits multiple variations of that gene. $A$ classic example of this phenomenon is the $ABO$ blood group system in humans,where the gene $I$ exists in three allelic forms: $I^A$,$I^B$,and $i$.
53
MediumMCQ
The gene $I$ that controls the $ABO$ blood grouping produces antigens on the surface of red blood cells. What are these antigens made of?
A
Protein
B
Polysaccharide
C
Lipid
D
Nucleic acid

Solution

(B) The gene $I$ controls the $ABO$ blood grouping in humans. This gene has three alleles: $I^A$,$I^B$,and $i$. The alleles $I^A$ and $I^B$ produce specific sugar polymers (polysaccharides) on the surface of the plasma membrane of red blood cells,which act as antigens. The allele $i$ does not produce any sugar. Therefore,these antigens are composed of polysaccharides.
54
MediumMCQ
In which of the following phenomena can both dominance and codominance be observed?
A
Blood grouping
B
Snapdragon plant
C
Mendelian dihybrid cross
D
All of the above

Solution

(A) In human $ABO$ blood grouping,the gene $I$ has three alleles: $I^A$,$I^B$,and $i$.
$I^A$ and $I^B$ are dominant over $i$,which shows the phenomenon of dominance.
When $I^A$ and $I^B$ are present together,both express themselves equally,which is the phenomenon of codominance.
Therefore,human blood grouping is the correct example where both dominance and codominance are observed.
55
MediumMCQ
Determine the number of possible phenotypes in the $ABO$ blood grouping system.
A
$3$
B
$6$
C
$4$
D
$5$

Solution

(C) In the $ABO$ blood grouping system,the inheritance is controlled by the gene $I$. The gene $I$ has three alleles: $I^A$,$I^B$,and $i$.
Because there are three alleles,the possible genotypes are $I^A I^A$,$I^A i$,$I^B I^B$,$I^B i$,$I^A I^B$,and $ii$ (total $6$ genotypes).
However,the phenotypes are determined by the expression of these alleles. The alleles $I^A$ and $I^B$ are dominant over $i$,and $I^A$ and $I^B$ are codominant with each other.
- Genotypes $I^A I^A$ and $I^A i$ result in blood type $A$.
- Genotypes $I^B I^B$ and $I^B i$ result in blood type $B$.
- Genotype $I^A I^B$ results in blood type $AB$.
- Genotype $ii$ results in blood type $O$.
Thus,there are $4$ possible phenotypes: $A$,$B$,$AB$,and $O$.
56
MediumMCQ
Which of the following characteristics can be expressed by $3$ alleles?
A
Incomplete dominance
B
Blood group
C
Dihybrid cross
D
Pleiotropy

Solution

(B) The $ABO$ blood grouping system in humans is a classic example of multiple allelism.
It is controlled by the gene $I$ (Isoagglutinogen).
The gene $I$ has $3$ alleles: $I^A$,$I^B$,and $i$.
These $3$ alleles determine the blood type of an individual based on the combinations present (e.g.,$I^A I^A$,$I^A i$,$I^B I^B$,$I^B i$,$I^A I^B$,and $ii$).
57
MediumMCQ
If both parents have blood group $AB$, which blood group cannot be found in their child?
A
$A, B, AB$
B
$A, B$
C
$O$
D
$AB$

Solution

(C) The blood group of an individual is determined by the $ABO$ gene, which has three alleles: $I^A$, $I^B$, and $i$.
Parents with blood group $AB$ have the genotype $I^A I^B$.
When these parents produce gametes, each gamete will carry either the $I^A$ allele or the $I^B$ allele.
Possible combinations for the offspring are:
$I^A \times I^A = I^A I^A$ (Blood group $A$)
$I^A \times I^B = I^A I^B$ (Blood group $AB$)
$I^B \times I^A = I^A I^B$ (Blood group $AB$)
$I^B \times I^B = I^B I^B$ (Blood group $B$)
Thus, the possible blood groups for the children are $A$, $B$, and $AB$.
The blood group $O$ (genotype $ii$) cannot be produced because neither parent carries the recessive $i$ allele.
58
MediumMCQ
In which of the following can multiple alleles be observed?
A
Codominance
B
Incomplete dominance
C
$ABO$ blood grouping
D
All of the above

Solution

(C) Multiple alleles refer to the existence of more than two alleles for a single gene locus within a population.
In the case of the $ABO$ blood grouping system in humans,the gene $I$ exists in three allelic forms: $I^A$,$I^B$,and $i$.
Since there are three alleles ($I^A$,$I^B$,and $i$) controlling a single trait (blood type),this is a classic example of multiple alleles.
Codominance and incomplete dominance are patterns of inheritance,but they do not define the presence of multiple alleles.
59
MediumMCQ
If a man with blood group $A$ marries a woman with blood group $AB$,which of the following offspring would indicate that the man is heterozygous for blood group $A$?
A
$AB$
B
$A$
C
$B$
D
$O$

Solution

(C) The genotype of a man with blood group $A$ can be either homozygous $(I^A I^A)$ or heterozygous $(I^A i)$.
The genotype of a woman with blood group $AB$ is $I^A I^B$.
If the man is homozygous $(I^A I^A)$,the possible offspring genotypes are $I^A I^A$ (blood group $A$) and $I^A I^B$ (blood group $AB$).
If the man is heterozygous $(I^A i)$,the possible offspring genotypes are $I^A I^A$ (blood group $A$),$I^A I^B$ (blood group $AB$),$I^A i$ (blood group $A$),and $I^B i$ (blood group $B$).
Therefore,the presence of an offspring with blood group $B$ $(I^B i)$ confirms that the father must carry the recessive allele $i$,meaning he is heterozygous $(I^A i)$.
60
MediumMCQ
Which of the following characteristics is true for the control of blood groups in humans?
A
$I^A$ and $I^B$ are two recessive alleles.
B
Three alleles $I^A$,$I^B$,and $i$ are involved.
C
All three alleles $I^A$,$I^B$,and $i$ are homozygous.
D
All three alleles $I^A$,$I^B$,and $i$ are dominant.

Solution

(B) In humans,the $ABO$ blood grouping is controlled by the gene $I$.
This gene has three alleles: $I^A$,$I^B$,and $i$.
$I^A$ and $I^B$ produce different forms of sugar polymers on the plasma membrane of red blood cells,while $i$ does not produce any sugar.
$I^A$ and $I^B$ are dominant over $i$,but $I^A$ and $I^B$ show codominance when present together.
Therefore,the correct characteristic is that three alleles $I^A$,$I^B$,and $i$ are involved in the control of blood groups.
61
MediumMCQ
If a man with blood group $A$ marries a woman with blood group $AB$, and their first child has blood group $B$, what is the genotype of the child?
A
$I^A I^B$
B
$I^A i$
C
$I^A I^A$
D
$I^B i$

Solution

(D) The father has blood group $A$, which can have the genotype $I^A I^A$ or $I^A i$.
The mother has blood group $AB$, which has the genotype $I^A I^B$.
The child has blood group $B$, which must have the genotype $I^B I^B$ or $I^B i$.
Since the child has blood group $B$, they must have inherited the $I^B$ allele from the mother.
To have blood group $B$, the child must have inherited an $i$ allele from the father (since the father cannot pass on an $I^B$ allele).
Therefore, the father's genotype must be $I^A i$.
The cross is $I^A i \times I^A I^B$.
The possible genotypes for the offspring are $I^A I^A$, $I^A I^B$, $I^A i$, and $I^B i$.
The child with blood group $B$ must have the genotype $I^B i$.
62
MediumMCQ
How many alleles determine the $A, B, AB,$ and $O$ blood groups in humans?
A
$1$
B
$2$
C
$3$
D
$6$

Solution

(C) The $ABO$ blood grouping in humans is controlled by the gene $I$.
This gene has three alleles: $I^A, I^B,$ and $i$.
- The alleles $I^A$ and $I^B$ produce slightly different forms of the sugar polymer on the surface of red blood cells,while the allele $i$ does not produce any sugar.
- Because there are three different alleles involved in determining the phenotype,this is an example of multiple allelism.
- Therefore,the correct number of alleles is $3$.
63
MediumMCQ
In the $ABO$ blood grouping system,what are the number of possible phenotypes and genotypes,respectively?
A
$4, 6$
B
$6, 4$
C
$3, 6$
D
$6, 3$

Solution

(A) In the $ABO$ blood grouping system,the inheritance is controlled by the gene $I$ which has three alleles: $I^A, I^B,$ and $i$.
$1$. Phenotypes: The possible blood groups are $A, B, AB,$ and $O$. Thus,there are $4$ possible phenotypes.
$2$. Genotypes: The possible combinations of these three alleles are $I^AI^A, I^Ai, I^BI^B, I^Bi, I^AI^B,$ and $ii$. Thus,there are $6$ possible genotypes.
Therefore,the number of phenotypes is $4$ and the number of genotypes is $6$.
64
MediumMCQ
Fill in the missing terms in the following statement: $ABO$ blood grouping explains codominance through ....... and dominance through .........
A
$I^A i, I^A I^A$
B
$I^A I^B, I^A I^A$
C
$I^A I^B, I^B i$
D
$I^A I^B, i i$

Solution

(C) In $ABO$ blood grouping,the gene $I$ has three alleles: $I^A, I^B,$ and $i$.
When $I^A$ and $I^B$ are present together,both express themselves equally,which is an example of codominance $(I^A I^B)$.
When $I^A$ or $I^B$ is present with $i$,the allele $i$ is recessive,and $I^A$ or $I^B$ shows dominance over $i$ (e.g.,$I^A i$ or $I^B i$).
Therefore,codominance is explained by $I^A I^B$ and dominance is explained by $I^B i$ (or $I^A i$).
65
MediumMCQ
The blood group of the father is $A$ and the blood group of the mother is $B$. Predict the possible blood groups of the progeny.
A
$A, AB$
B
$A, B, AB, O$
C
$B, AB$
D
$O, A, B$

Solution

(B) The inheritance of $ABO$ blood groups is controlled by the gene $I$. The gene $I$ has three alleles: $I^A, I^B,$ and $i$.
If the father has blood group $A$, his genotype can be $I^A I^A$ or $I^A i$.
If the mother has blood group $B$, her genotype can be $I^B I^B$ or $I^B i$.
Considering the heterozygous condition $(I^A i \times I^B i)$, the possible genotypes of the progeny are $I^A I^B$ $(AB)$, $I^A i$ $(A)$, $I^B i$ $(B)$, and $ii$ $(O)$.
Therefore, the possible blood groups of the progeny are $A, B, AB,$ and $O$.
66
MediumMCQ
Sometimes,there are more than two alleles for a given chromosome locus. In this case,a trait is said to be governed by:
A
Codominance
B
Pseudodominance
C
Incomplete dominance
D
Multiple alleles

Solution

(D) When more than two alleles exist for a specific gene locus within a population,the phenomenon is known as $Multiple \ alleles$.
This occurs because while an individual can only carry two alleles,the population as a whole can possess several variations of a gene,leading to a wider range of possible phenotypes.
67
MediumMCQ
Mother is homozygous for blood group $B$,and father has blood group $A$ (genotype unknown). Therefore,the possible blood groups in the progeny are:
A
$AB$ and $B$ possible
B
$AB$ and $A$ possible
C
$A$ and $B$ possible
D
$O$ possible

Solution

(A) The mother is homozygous for blood group $B$,so her genotype is $I^B I^B$. The father has blood group $A$,which could be homozygous $(I^A I^A)$ or heterozygous $(I^A I^O)$.
If the father is $I^A I^A$,the cross is $I^B I^B \times I^A I^A$,resulting in $I^A I^B$ (blood group $AB$).
If the father is $I^A I^O$,the cross is $I^B I^B \times I^A I^O$,resulting in $I^A I^B$ (blood group $AB$) and $I^B I^O$ (blood group $B$).
Combining these possibilities,the progeny can have blood groups $AB$ and $B$.
Solution diagram
68
MediumMCQ
The $ABO$ blood group is controlled by:
A
$I$-gene
B
$c$-gene
C
$B$-gene
D
$n$-gene

Solution

(A) The $ABO$ blood group in humans is controlled by the $I$ gene.
This gene exists in three allelic forms: $I^A$,$I^B$,and $i$.
- The alleles $I^A$ and $I^B$ produce slightly different forms of the sugar polymer that protrudes from the surface of the plasma membrane of red blood cells.
- The allele $i$ does not produce any sugar.
- Because humans are diploid organisms,each person possesses any two of the three $I$ gene alleles.
69
MediumMCQ
The plasma membrane of the red blood cells has ...$A$... polymers that protrude from its surface and the kind of sugar is controlled by the gene. The gene $I$ has three alleles ...$B$... The alleles and produce a slightly different form of the sugars,while allele $i$ doesn't produce any ...$C$...
Choose the correct option for $A, B$ and $C$.
A
$A-$protein,$B-I^{A} I^{B} I^{O}$,$C-$protein
B
$A-$protein,$B-I^{A} I^{B} I^{O}$,$C-$sugar
C
$A-$sugar,$B-I^{A} I^{B} I^{O}$,$C-$protein
D
$A-$sugar,$B-I^{A} I^{B} I^{O}$,$C-$sugar

Solution

(D) The plasma membrane of red blood cells has sugar polymers that protrude from its surface.
The kind of sugar is controlled by the gene $I$.
The gene $I$ has three alleles: $I^{A}, I^{B},$ and $i$.
The alleles $I^{A}$ and $I^{B}$ produce a slightly different form of the sugar,while the allele $i$ does not produce any sugar.
Therefore,$A$ is sugar,$B$ is $I^{A}, I^{B}, i$ (often represented as $I^{A}, I^{B}, I^{O}$),and $C$ is sugar.
The correct option is $D$.
70
MediumMCQ
$A$ man of blood group-$A$ marries a woman of blood group-$B$. Both of them are heterozygous for their blood group. The chances of their first child having blood group $AB$ will be: (in $, \%$)
A
$25$
B
$50$
C
$75$
D
$100$

Solution

(A) The man is heterozygous for blood group-$A$,so his genotype is $I^A I^O$.
The woman is heterozygous for blood group-$B$,so her genotype is $I^B I^O$.
When these two individuals cross $(I^A I^O \times I^B I^O)$,the possible genotypes of the offspring are:
$1. I^A I^B$ (Blood group $AB$)
$2. I^A I^O$ (Blood group $A$)
$3. I^B I^O$ (Blood group $B$)
$4. I^O I^O$ (Blood group $O$)
Each genotype has a probability of $25\, \%$. Therefore,the chance of the first child having blood group $AB$ is $25\, \%$.
Solution diagram
71
MediumMCQ
How many phenotypes and genotypes are possible in $ABO$ blood group systems?
A
Four,five
B
Four,six
C
Four,seven
D
Three,four

Solution

(B) The correct answer is $B$ (Four,six).
$ABO$ blood groups in humans are controlled by the gene $I$. The gene $I$ has three alleles: $I^{A}$,$I^{B}$,and $i$.
$1.$ The alleles $I^{A}$ and $I^{B}$ produce slightly different forms of sugar,while the allele $i$ does not produce any sugar.
$2.$ Because humans are diploid,each individual possesses any two of these three alleles. This results in the following six possible genotypes: $I^{A}I^{A}$,$I^{A}i$,$I^{B}I^{B}$,$I^{B}i$,$I^{A}I^{B}$,and $ii$.
$3.$ Due to the dominance relationships ($I^{A}$ and $I^{B}$ are dominant over $i$,and $I^{A}$ and $I^{B}$ are codominant with each other),these six genotypes result in four distinct phenotypes: $A$,$B$,$AB$,and $O$.
Genotype of OffspringBlood Type of Offspring
$I^{A}I^{A}$$A$
$I^{A}i$$A$
$I^{B}I^{B}$$B$
$I^{B}i$$B$
$I^{A}I^{B}$$AB$
$ii$$O$
72
EasyMCQ
In humans,four phenotypes of blood groups are due to the presence of antigen-$A$ and antigen-$B$ on the $RBC$. The chromosome that carries the gene controlling these antigens is:
A
$X$-chromosome
B
$21^{\text{st}}$ chromosome
C
$9^{\text{th}}$ chromosome
D
$7^{\text{th}}$ chromosome

Solution

(C) The $ABO$ blood grouping in humans is controlled by the gene $I$ (isoagglutinogen). This gene $I$ is located on the $9^{\text{th}}$ chromosome. The gene $I$ has three alleles: $I^A$,$I^B$,and $i$. The combination of these alleles determines the phenotype of the blood group ($A$,$B$,$AB$,or $O$).
73
MediumMCQ
What will be the possible blood groups in children from parents with $B$ and $AB$ blood groups?
A
$A, O$
B
$A, B, AB \;\&\; O$
C
$A, B, AB$
D
$B, O$

Solution

(C) The blood group of parents are $B$ and $AB$.
If the parent with blood group $B$ is heterozygous $(I^Bi)$ and the parent with blood group $AB$ is $(I^AI^B)$,the cross is as follows:
$I^Bi \times I^AI^B$
Gametes: $(I^B, i)$ and $(I^A, I^B)$
Possible genotypes of offspring: $I^AI^B$ $(AB)$,$I^BI^B$ $(B)$,$I^Ai$ $(A)$,$I^Bi$ $(B)$.
Thus,the possible blood groups in children are $A, B,$ and $AB$.
Solution diagram
74
MediumMCQ
Progeny with blood group '$O$' cannot be obtained in which of the following crosses?
A
$A \times A$
B
$A \times B$
C
$O \times AB$
D
$B \times B$

Solution

(C) The blood group '$O$' is determined by the genotype $ii$.
In the cross $O \times AB$,the parents have genotypes $ii$ and $I^A I^B$ respectively.
The gametes produced are $i$ from the $O$ parent and $I^A$ or $I^B$ from the $AB$ parent.
The resulting offspring will have genotypes $I^A i$ (blood group $A$) or $I^B i$ (blood group $B$).
Therefore,it is impossible to obtain an offspring with blood group '$O$' $(ii)$ from this cross.
75
Difficult
Explain Multiple Alleles and the concept of Dominance with an example.

Solution

(N/A) $1$. Multiple Alleles: In this case,more than two,i.e.,three or more alleles are present governing the same character. Multiple alleles can be found only when population studies are conducted.
$2$. Dominance: Dominance is not an autonomous feature of a gene or the product that it has information for. It depends on the gene product and the production of a particular phenotype from this product,as well as the particular phenotype that we choose to examine.
$3$. Example (Starch synthesis in pea seeds): Starch synthesis in pea seeds is controlled by one gene with two alleles ($B$ and $b$).
- $BB$ homozygotes synthesize starch effectively,producing large starch grains (Round seeds).
- $bb$ homozygotes have lower efficiency,producing smaller starch grains (Wrinkled seeds).
- Heterozygotes $(Bb)$ produce round seeds,suggesting $B$ is dominant for seed shape.
- However,the starch grains in $Bb$ seeds are of intermediate size. Thus,if starch grain size is the phenotype,the alleles show incomplete dominance.
- This demonstrates that dominance depends on the phenotype chosen for examination.
76
MediumMCQ
In Mendel's monohybrid cross,$T$ and $t$ are ......... of each other.
A
Genes
B
Factors
C
Alleles
D
All of the above

Solution

(C) In Mendel's experiments,the traits are controlled by discrete units called factors.
These factors occur in pairs.
When these factors represent two different forms of the same gene,they are referred to as alleles.
In the case of height,$T$ (tall) and $t$ (dwarf) are two different forms of the same gene,hence they are alleles of each other.
77
MediumMCQ
Which of the following is an example of multiple alleles?
A
$ABO$ blood grouping
B
Flower color in snapdragon
C
Coat color in cattle
D
All of the above

Solution

(A) Multiple alleles refer to the presence of more than two alternative forms of a gene in a population.
$ABO$ blood grouping in humans is a classic example of multiple alleles,where the gene $I$ exists in three allelic forms: $I^A$,$I^B$,and $i$.
Flower color in snapdragon ($Antirrhinum$ $sp.$) is an example of incomplete dominance.
Coat color in cattle is an example of codominance.
Therefore,only $ABO$ blood grouping represents multiple alleles.
78
MediumMCQ
In $ABO$ blood grouping,there are $P$ genotypes and $Q$ phenotypes.
$\quad P \quad\quad Q$
A
$6 \quad\quad 6$
B
$4 \quad\quad 4$
C
$6 \quad\quad 4$
D
$4 \quad\quad 6$

Solution

(C) In $ABO$ blood grouping,the inheritance is controlled by the gene $I$. The gene $I$ has three alleles: $I^A, I^B,$ and $i$.
Because there are three alleles,the possible genotypes are $I^A I^A, I^A i, I^B I^B, I^B i, I^A I^B,$ and $ii$. Thus,there are $6$ genotypes.
The possible phenotypes are $A, B, AB,$ and $O$. Thus,there are $4$ phenotypes.
Therefore,$P = 6$ and $Q = 4$.
79
MediumMCQ
$A$ male with heterozygous blood group $B$ and a female with homozygous blood group $A$ have offspring. What are the possible genotypes and phenotypes in their progeny?
A
$2, 2$
B
$4, 4$
C
$4, 2$
D
$2, 4$

Solution

(A) The genotype of a male with heterozygous blood group $B$ is $I^B i$.
The genotype of a female with homozygous blood group $A$ is $I^A I^A$.
Crossing these: $I^A I^A \times I^B i$.
The resulting genotypes are $I^A I^B$ and $I^A i$.
$1$. Genotypes: $I^A I^B$ ($AB$ blood group) and $I^A i$ ($A$ blood group). There are $2$ distinct genotypes.
$2$. Phenotypes: $AB$ blood group and $A$ blood group. There are $2$ distinct phenotypes.
Therefore,the number of genotypes is $2$ and the number of phenotypes is $2$.
80
MediumMCQ
What are the products of the $I^A$ and $I^B$ alleles?
A
Protein
B
Carbohydrate
C
Lipid
D
Nucleic acid

Solution

(B) The $I^A$ and $I^B$ alleles code for enzymes (glycosyltransferases) that add specific sugar molecules to the surface of red blood cells.
These sugar molecules are carbohydrates (specifically,oligosaccharides) that act as antigens on the surface of the plasma membrane of red blood cells.
Therefore,the products of these alleles are carbohydrates.
81
EasyMCQ
On which chromosome are the genes for the $ABO$ blood group located?
A
Third
B
Seventh
C
Ninth
D
Twentieth

Solution

(C) The $ABO$ blood group system in humans is controlled by the $I$ gene. This gene is located on the long arm of chromosome number $9$ $(9q34.2)$. The gene has three alleles: $I^A$,$I^B$,and $i$.
82
MediumMCQ
$A$ couple has four children with blood groups $A, AB, A,$ and $O$ respectively. What are the genotypes of the parents' blood groups?
A
$I^B i$ and $I^A I^B$
B
$I^A I^B$ and $ii$
C
$I^A i$ and $I^B I^B$
D
$I^A i$ and $I^B i$

Solution

(D) The blood groups of the children are $A, AB, A,$ and $O$.
For a child to have blood group $O$ $(ii)$,both parents must contribute an $i$ allele. Thus,both parents must be heterozygous.
For a child to have blood group $AB$ $(I^A I^B)$,one parent must contribute $I^A$ and the other must contribute $I^B$.
Combining these requirements,the parents must have genotypes $I^A i$ (Blood group $A$) and $I^B i$ (Blood group $B$).
Cross: $I^A i \times I^B i$ results in offspring with genotypes $I^A I^B$ $(AB)$,$I^A i$ $(A)$,$I^B i$ $(B)$,and $ii$ $(O)$.
Since the children include $A, AB,$ and $O$,the parents must be $I^A i$ and $I^B i$.
83
MediumMCQ
In which of the following crosses will the offspring show the greatest diversity in phenotypes?
A
$I^A i$ and $I^B i$
B
$I^A I^A$ and $I^B i$
C
$I^A I^B$ and $ii$
D
$I^A i$ and $I^A I^B$

Solution

(A) To determine the greatest phenotypic diversity,we analyze the possible blood types for each cross:
$1$. $I^A i \times I^B i$: Offspring can be $I^A I^B$ $(AB)$,$I^A i$ $(A)$,$I^B i$ $(B)$,and $ii$ $(O)$. This results in $4$ distinct phenotypes.
$2$. $I^A I^A \times I^B i$: Offspring can be $I^A I^B$ $(AB)$ and $I^A i$ $(A)$. This results in $2$ distinct phenotypes.
$3$. $I^A I^B \times ii$: Offspring can be $I^A i$ $(A)$ and $I^B i$ $(B)$. This results in $2$ distinct phenotypes.
$4$. $I^A i \times I^A I^B$: Offspring can be $I^A I^A$ $(A)$,$I^A i$ $(A)$,$I^A I^B$ $(AB)$,and $I^B i$ $(B)$. This results in $3$ distinct phenotypes.
Therefore,the cross $I^A i \times I^B i$ produces the maximum number of phenotypes $(4)$.
84
MediumMCQ
As per the $ABO$ blood grouping system,the blood group of the father is $B^{+}$,the mother is $A^{+}$,and the child is $O^{+}$. Their respective genotypes can be:
Choose the most appropriate answer from the options given below:
$A. I^Bi / I^Ai / ii$
$B. I^BI^B / I^AI^A / ii$
$C. I^AI^B / iI^A / I^Bi$
$D. I^Ai / I^Bi / I^Ai$
$E. iI^B / iI^A / I^AI^B$
Question diagram
A
$B$ only
B
$C, B$ only
C
$D, E$ only
D
$A$ only

Solution

(D) In the $ABO$ blood grouping system,the alleles are $I^A, I^B,$ and $i$.
For a child to have blood group $O$ (genotype $ii$),they must inherit one $i$ allele from each parent.
Therefore,the father (blood group $B$) must have the genotype $I^Bi$ and the mother (blood group $A$) must have the genotype $I^Ai$.
Looking at the provided options:
$A$ represents $I^Bi$ (Father),$I^Ai$ (Mother),and $ii$ (Child),which is consistent with the blood groups given.
Thus,only option $A$ is correct.
85
EasyMCQ
The following table is regarding $ABO$ blood group. Identify $W, X, Y, Z$.
GenotypeBlood group
$I^{A} I^{A}$$A$
$W$$A$
$I^{B} I^{B}$$B$
$X$$B$
$I^{A} I^{B}$$Y$
$Z$$O$
A
$W \rightarrow I^{A} I^0, X \rightarrow I^{B} I^0, Y \rightarrow I^0 I^0, Z \rightarrow AB$
B
$W \rightarrow I^{A} I^0, X \rightarrow I^{B} I^0, Y \rightarrow AB, Z \rightarrow I^0 I^0$
C
$W \rightarrow I^{B} I^0, X \rightarrow I^{A} I^0, Y \rightarrow AB, Z \rightarrow I^0 I^0$
D
$W \rightarrow I^{B} I^{A}, X \rightarrow I^{A} I^{A}, Y \rightarrow AB, Z \rightarrow I^0 I^0$

Solution

(B) In the $ABO$ blood group system,the gene $I$ has three alleles: $I^A, I^B,$ and $i$ (or $I^0$).
$1$. For blood group $A$,the genotypes are $I^A I^A$ or $I^A i$. Thus,$W = I^A i$ (or $I^A I^0$).
$2$. For blood group $B$,the genotypes are $I^B I^B$ or $I^B i$. Thus,$X = I^B i$ (or $I^B I^0$).
$3$. For the genotype $I^A I^B$,both alleles are expressed equally,resulting in blood group $AB$. Thus,$Y = AB$.
$4$. For blood group $O$,the genotype is $ii$ (or $I^0 I^0$). Thus,$Z = I^0 I^0$.
Therefore,the correct identification is $W \rightarrow I^A I^0, X \rightarrow I^B I^0, Y \rightarrow AB, Z \rightarrow I^0 I^0$.
86
MediumMCQ
Which one of the following blood groups is expressed in both homozygous and heterozygous conditions?
A
Only $A$
B
Only $B$
C
$A$ and $B$
D
$O$

Solution

(C) In the $ABO$ blood grouping system,the alleles $I^A$ and $I^B$ are dominant over the allele $i$.
- Blood group $A$ is expressed in homozygous $(I^A I^A)$ and heterozygous $(I^A i)$ conditions.
- Blood group $B$ is expressed in homozygous $(I^B I^B)$ and heterozygous $(I^B i)$ conditions.
- Blood group $O$ is only expressed in the homozygous $(ii)$ condition.
- Therefore,both blood groups $A$ and $B$ are expressed in both homozygous and heterozygous conditions.
87
MediumMCQ
With respect to $\text{ABO}$ blood groups,how many genotypes and phenotypes,respectively,are possible in the human population?
A
$6 \ \& \ 4$
B
$4 \ \& \ 6$
C
$3 \ \& \ 4$
D
$4 \ \& \ 3$

Solution

(A) The $\text{ABO}$ blood grouping in humans is controlled by the gene $I$. The gene $I$ has three alleles: $I^A$,$I^B$,and $i$.
Since there are three alleles,the possible genotypes are determined by the combinations of these alleles taken two at a time (including homozygotes). These are: $I^A I^A$,$I^A i$,$I^B I^B$,$I^B i$,$I^A I^B$,and $ii$. Thus,there are $6$ possible genotypes.
The phenotypes are determined by the expression of these alleles. $I^A$ and $I^B$ are dominant over $i$,and $I^A$ and $I^B$ are codominant with each other. The possible phenotypes are: Blood group $A$ (from $I^A I^A$ or $I^A i$),Blood group $B$ (from $I^B I^B$ or $I^B i$),Blood group $AB$ (from $I^A I^B$),and Blood group $O$ (from $ii$). Thus,there are $4$ possible phenotypes.
Therefore,the number of genotypes is $6$ and the number of phenotypes is $4$.
88
MediumMCQ
Which of the following characteristics represent 'Inheritance' of blood group in humans $:-$
$(a)$ $ABO$ blood groups are controlled by the gene $I$.
$(b)$ Plasma membrane of the red blood cells has sugar polymers that protrude from its surface.
$(c)$ The gene $I$ has three alleles i.e.,$I^A, I^B$ and $i$. Each diploid person possesses any two alleles of gene $I$.
$(d)$ There are six different possible combinations of three alleles of gene $I$.
$(e)$ '$O$' blood group is not possible in the progeny of '$AB$' blood group parents.
A
Only $a$ and $e$
B
Only $b, c$ and $d$
C
Only $b$ and $d$
D
Only $a, c$ and $e$

Solution

(A) Let's analyze each statement:
$(a)$ $ABO$ blood groups are indeed controlled by the gene $I$. This is correct.
$(b)$ The plasma membrane of red blood cells has sugar polymers that protrude from its surface,not amino polymers. This is incorrect.
$(c)$ The gene $I$ has three alleles $(I^A, I^B, i)$. However,a diploid person only possesses any two of these alleles,not all three. This is incorrect.
$(d)$ There are six possible genotypes for the three alleles $(I^A I^A, I^A i, I^B I^B, I^B i, I^A I^B, ii)$. This is incorrect as the statement claims eight.
$(e)$ Parents with '$AB$' blood group $(I^A I^B)$ can produce children with '$A$','$B$',or '$AB$' blood groups,but not '$O$' $(ii)$. This is correct.
Therefore,statements $(a)$ and $(e)$ are correct.
89
EasyMCQ
Considering the concept of multiple alleles,one individual can have only . . . . . . alleles for that character.
A
one
B
two
C
three
D
four

Solution

(B) Multiple alleles refer to the existence of more than two alternative forms of a gene within a population.
However,because an individual is a diploid organism,they possess only two homologous chromosomes.
Therefore,any single individual can carry only two alleles for a specific character at a given locus,even if many more alleles exist in the population.
For example,in the $ABO$ blood grouping system,there are three alleles $(I^A, I^B, i)$,but an individual can only possess two of these.
90
EasyMCQ
In humans,multiple alleles are seen controlling the inheritance of which of the following?
A
Sickle cell anaemia
B
Blood groups
C
Colour blindness
D
Thalassemia

Solution

(B) The $ABO$ blood group system in humans is a classic example of multiple alleles. It is determined by three alleles: $I^A$,$I^B$,and $i$. The presence of different combinations of these three alleles results in four different blood types: $A$,$B$,$AB$,and $O$.
91
EasyMCQ
If the father has $AB$ blood group and mother has $A$ blood group,then the children born to them will have the following blood groups $EXCEPT$ . . . . . . .
A
$AB$
B
$A$
C
$O$
D
$B$

Solution

(C) The father has blood group $AB$,which means his genotype is $I^A I^B$. The mother has blood group $A$,which means her genotype can be either $I^A I^A$ or $I^A i$.
If the mother is $I^A I^A$,the possible offspring genotypes are $I^A I^A$ (Blood group $A$) and $I^A I^B$ (Blood group $AB$).
If the mother is $I^A i$,the possible offspring genotypes are $I^A I^A$ (Blood group $A$),$I^A i$ (Blood group $A$),$I^A I^B$ (Blood group $AB$),and $I^B i$ (Blood group $B$).
In both cases,the allele $i$ (which is required for blood group $O$ genotype $ii$) cannot be formed because the father does not carry the $i$ allele. Therefore,it is impossible for the children to have blood group $O$.
92
EasyMCQ
How many of the following genotypes possibly represent normal wings in Drosophila?
$(i)$ $Vg^{+} Vg^{+}$
(ii) $Vg^{+} vg^{ni}$
(iii) $Vg^{+} vg^{no}$
(iv) $Vg^{+} vg^{st}$
$(v)$ $Vg^{+} vg$
A
$(i)$,(ii) and (iii) only
B
$(i)$ and (ii) only
C
Only $(i)$
D
$(i)$,(ii),(iii),(iv) and $(v)$

Solution

(D) In $Drosophila$,the wild-type allele for wing shape is denoted as $Vg^{+}$.
This wild-type allele is dominant over all other mutant alleles (such as $vg^{ni}$,$vg^{no}$,$vg^{st}$,and $vg$).
Since all the given genotypes contain at least one $Vg^{+}$ allele,they will all express the dominant wild-type phenotype,which is normal wings.
Therefore,all five genotypes represent normal wings in $Drosophila$.
93
EasyMCQ
If the blood group of the mother is $A$ and the blood group of the father is $O$,what may be the blood group of the progeny?
A
$A, AB, B, O$
B
$A$ or $B$
C
$A$ or $O$
D
Only blood group $A$

Solution

(C) The blood group of the mother is $A$,which can have the genotype $I^A I^A$ or $I^A i$. The blood group of the father is $O$,which has the genotype $ii$.
If the mother is $I^A I^A$,the progeny will have genotypes $I^A i$ (Blood group $A$).
If the mother is $I^A i$,the progeny will have genotypes $I^A i$ (Blood group $A$) and $ii$ (Blood group $O$).
Therefore,the possible blood groups of the progeny are $A$ or $O$.
94
EasyMCQ
The blood group of Rameshbhai is $B$ and his daughter's blood group is $AB$. What will be the blood group of his wife?
A
$B$ or $O$
B
$A$ or $AB$
C
$A$ or $B$
D
$A$ or $O$

Solution

(B) The blood group of Rameshbhai is $B$,which means his genotype can be either $I^B I^B$ or $I^B i$.
The daughter's blood group is $AB$,which means her genotype is $I^A I^B$.
Since the daughter must inherit one allele from each parent,she must have received the $I^A$ allele from her mother and the $I^B$ allele from her father.
Therefore,the mother must possess at least one $I^A$ allele.
Possible blood groups for the mother that contain the $I^A$ allele are $A$ ($I^A I^A$ or $I^A i$) or $AB$ $(I^A I^B)$.
95
EasyMCQ
If the father gives $I^B$ allele and the mother gives $I^A$ allele,state the genotype and blood group of the offspring.
A
$I^A I^B - AB$
B
$I^A I^B - A$
C
$I^A I^B - B$
D
$I^A I^A - AB$

Solution

(A) In human blood group inheritance,the $ABO$ blood group system is controlled by the gene $I$. The gene $I$ has three alleles: $I^A$,$I^B$,and $i$.
When the father contributes the $I^B$ allele and the mother contributes the $I^A$ allele,the resulting genotype of the offspring is $I^A I^B$.
According to the principle of codominance,both $I^A$ and $I^B$ alleles are expressed equally in the presence of each other.
Therefore,the individual with the genotype $I^A I^B$ will have blood group $AB$.
96
EasyMCQ
What is the possible blood group of children whose parents are heterozygous for $A$ and $B$ blood groups?
A
$A$,$B$ only
B
$A$,$B$,$AB$ and $O$
C
$AB$ only
D
$A$,$B$ and $AB$ only

Solution

(B) The correct answer is $B$.
Parents are heterozygous for blood groups $A$ and $B$,meaning their genotypes are $I^A i$ and $I^B i$.
When these parents cross,the possible combinations of alleles in the offspring are:
$1. I^A I^B$ (Blood group $AB$)
$2. I^A i$ (Blood group $A$)
$3. I^B i$ (Blood group $B$)
$4. ii$ (Blood group $O$)
Therefore,the children can have any of the four blood groups: $A, B, AB,$ or $O$.
97
EasyMCQ
The genotypes of a husband and wife are $I^A I^B$ and $I^A I^O$. Among the blood types of their children,how many different genotypes and phenotypes are possible?
A
$3$ genotypes; $3$ phenotypes
B
$4$ genotypes; $3$ phenotypes
C
$4$ phenotypes; $3$ genotypes
D
$4$ phenotypes; $4$ genotypes

Solution

(B) The genotypes of the parents are $I^A I^B$ (husband) and $I^A I^O$ (wife).
To find the possible genotypes of the offspring,we perform a Punnett square cross:
- $I^A$ from father $\times$ $I^A$ from mother $\rightarrow$ $I^A I^A$ (Blood type $A$)
- $I^A$ from father $\times$ $I^O$ from mother $\rightarrow$ $I^A I^O$ (Blood type $A$)
- $I^B$ from father $\times$ $I^A$ from mother $\rightarrow$ $I^A I^B$ (Blood type $AB$)
- $I^B$ from father $\times$ $I^O$ from mother $\rightarrow$ $I^B I^O$ (Blood type $B$)
Possible genotypes: $I^A I^A, I^A I^O, I^A I^B, I^B I^O$ (Total $4$ genotypes).
Possible phenotypes: Blood type $A$,Blood type $AB$,Blood type $B$ (Total $3$ phenotypes).
Therefore,the correct answer is $4$ genotypes and $3$ phenotypes.
98
EasyMCQ
$A$ man with blood group $A$ marries a woman having blood group $B$. The maximum possible blood groups among their progenies are
A
$A, B, AB, O$
B
$AB$ only
C
$A, B, AB$
D
$A, B$

Solution

(A) The inheritance of $ABO$ blood groups is controlled by the gene $I$. The gene $I$ has three alleles: $I^A, I^B,$ and $i$.
If the man is heterozygous $(I^Ai)$ and the woman is heterozygous $(I^Bi)$,the cross is $I^Ai \times I^Bi$.
The possible genotypes of the offspring are $I^AI^B$ (blood group $AB$),$I^Ai$ (blood group $A$),$I^Bi$ (blood group $B$),and $ii$ (blood group $O$).
Therefore,the maximum possible blood groups among their children are $A, B, AB,$ and $O$.
99
EasyMCQ
The offspring produced from a marriage have only $O$ or $A$ blood groups. Of the genotypes given below,the possible genotypes of the parents would be
A
$I^{A}I^{A}$ and $I^{O}I^{O}$
B
$I^{A}I^{O}$ and $I^{O}I^{O}$
C
$I^{A}I^{A}$ and $I^{A}I^{O}$
D
$I^{O}I^{O}$ and $I^{O}I^{O}$

Solution

(B) The correct option is $(B) I^{A}I^{O}$ and $I^{O}I^{O}$.
For the offspring to have only $A$ or $O$ blood groups,one parent must have the genotype $I^{A}I^{O}$ (blood group $A$) and the other must have $I^{O}I^{O}$ (blood group $O$).
When these parents are crossed,the possible genotypes of the offspring are $I^{A}I^{O}$ (blood group $A$) and $I^{O}I^{O}$ (blood group $O$).
This confirms that the offspring will only possess blood groups $A$ or $O$.
Solution diagram
100
MediumMCQ
What is the probability of having children with '$O$' blood group,where both mother and father are heterozygous for '$A$' and '$B$' blood group,respectively?
A
$(1)$ $0$%
B
$(2)$ $50$%
C
$(3)$ $25$%
D
$(4)$ $75$%

Solution

(C) The mother is heterozygous for blood group '$A$',represented by the genotype $I^A i$.
The father is heterozygous for blood group '$B$',represented by the genotype $I^B i$.
Performing the genetic cross: $(I^A i) \times (I^B i)$.
The possible offspring genotypes are:
$1$. $I^A I^B$ (Blood group $AB$)
$2$. $I^A i$ (Blood group $A$)
$3$. $I^B i$ (Blood group $B$)
$4$. $ii$ (Blood group $O$)
Out of the four possible outcomes,only one results in blood group '$O$'.
Therefore,the probability of having a child with blood group '$O$' is $\frac{1}{4} = 25\%$.

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