Which of the following peptide chain is remov | vedclass

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Question

Insulin contains two short polypeptide chains, chain $A$ and $B$-chain linked by disulphide bridge. In mammals, insulin is synthesised as prohormone (

Vedclass · Accepted Answer

$C-$chain ( $33$ amino acid)

Vedclass · Answer

Insulin contains two short polypeptide chains, chain $A$ and $B$-chain linked by disulphide bridge. In mammals, insulin is synthesised as prohormone (that needs to be processed to become mature and functional hormone). It contains an extra stretch called-peptide. $C-$peptide is absent in mature insulin and is removed during the maturation into insulin

Which of the following peptide chain is removed during the maturation of proinsulin into insulin?

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