The defect sickle-cell anaemia is caused by the ______ of glutamic acid by valine at the $6^{th}$ position of the ______ globin chain of the haemoglobin molecule.
The defect sickle-cell anaemia is caused by the ______ of glutamic acid by valine at the $6^{th}$ position of the ______ globin chain of the haemoglobin molecule.
- A
Substitution, $\beta$
- B
Deletion, $\alpha$
- C
Duplication, $\beta$
- D
Translocation, $\alpha$
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