| Column-$I$ | Column-$II$ |
|---|---|
| $(A)$ $\text{YAC}$ | $(I)$ Separation of $\text{DNA}$ fragments |
| $(B)$ $\text{Hind II}$ | $(II)$ Yeast |
| $(C)$ Gel electrophoresis | $(III)$ First restriction endonuclease |
| $(D)$ Heterologous host | $(IV)$ Recombinant protein |
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