In India,the first international meeting on biotechnology was held in which year?

Select the correct match for $X$ and $Y$:

Column $X$	Column $Y$
$(1)$ Orchid	$(P)$ Undifferentiated mass of cells
$(2)$ Methylophilus methylotrophus	$(Q)$ Twice the amount of lysine and tryptophan
$(3)$ Callus	$(R)$ High rate of protein production
$(4)$ Hybrid maize	$(S)$ Embryo rescue

Match the following columns:

Column-$I$	Column-$II$
$(a)$ Pest resistant plant	$(1)$ Transgenic cow
$(b)$ Golden rice	$(2)$ $C$-peptide
$(c)$ Proinsulin	$(3)$ High vitamin $A$ content
$(d)$ Rosie	$(4)$ $RNA$ interference

Statement $I$: $\text{RNA}$ interference $\text{(RNAi)}$ takes place in all eukaryotic organisms as a method of cellular defense.
Statement $II$: $Bt$ toxin protein is converted into an active form of toxin due to the alkaline $pH$ of the gut of an insect.

Which of the following is $NOT$ a biotechnological product?

Read the following four statements $(1-4)$ and identify the two statements that contain mistakes:
$1.$ The first transgenic buffalo,Rosie,produced milk which was human alpha-lactalbumin enriched.
$2.$ Restriction enzymes are used in the isolation of $DNA$ from other macromolecules.
$3.$ Downstream processing is one of the steps of $R-DNA$ technology.
$4.$ Disarmed pathogen vectors are also used in the transfer of $R-DNA$ into the host.
Which are the two statements having mistakes?