Explain the $EMP$ (Embden,Meyerhof,and Parnas) pathway.

Vedclass pdf generator app on play store
Vedclass iOS app on app store
(N/A) The $EMP$ pathway,commonly known as glycolysis,is the process of breaking down one molecule of glucose into two molecules of pyruvic acid. It occurs in the cytoplasm of the cell.
Key steps of the $EMP$ pathway:
$1$. Phosphorylation: Glucose is phosphorylated to Glucose-$6$-phosphate by the enzyme hexokinase,consuming one $ATP$.
$2$. Isomerization: Glucose-$6$-phosphate isomerizes to Fructose-$6$-phosphate.
$3$. Second Phosphorylation: Fructose-$6$-phosphate is converted to Fructose-$1,6$-bisphosphate,consuming another $ATP$.
$4$. Cleavage: Fructose-$1,6$-bisphosphate splits into two $3$-carbon molecules: Dihydroxyacetone phosphate $(DHAP)$ and $3$-phosphoglyceraldehyde ($PGAL$ or $G3P$).
$5$. Oxidation and Phosphorylation: $PGAL$ is oxidized to $1,3$-bisphosphoglycerate $(BPGA)$,reducing $NAD^+$ to $NADH + H^+$.
$6$. $ATP$ Generation: $BPGA$ is converted to $3$-phosphoglyceric acid $(PGA)$,generating $ATP$.
$7$. Final Steps: Through a series of reactions,$PGA$ is converted to Phosphoenolpyruvate $(PEP)$,and finally to Pyruvic acid,generating another $ATP$ per molecule.
Net yield per glucose molecule: $2$ Pyruvic acid,$2$ $ATP$ (net),and $2$ $NADH + H^+$.

Explore More

Similar Questions

Given below are two statements:
$Statement-I$: Glycolysis is a common step in anaerobic as well as aerobic respiration and it occurs in the mitochondrial matrix.
$Statement-II$: The first five steps of glycolysis constitute its preparatory phase.
In the light of the above statements,choose the correct answer from the options given below.

Glycolysis is found in the cytoplasm of virtually all types of aerobic and anaerobic cells. In this process,glucose is converted into a compound which is:

Identify $A$ and $B$ respectively from the given glycolysis pathway.

Which enzyme of glycolysis is also called as the pacemaker enzyme?

Number of $ATP$ molecules formed in glycolysis by substrate-level phosphorylation is . . . . . . .

Vedclass Products

For Students

Vedclass Test Series

Mock tests in real JEE/NEET style with performance analysis. 5-day free trial.

Start Free Trial
For Teachers

Exam Paper Generator

Generate Set A/B/C/D exam papers from 7.5L+ questions in 2 minutes. 3 chapters free.

Try Free
For Institutes

Online Exam Module

Live online exams with unlimited students, 360° analytics & white-label branding.

See Demo