(N/A) Down's SyndromeKlinefelter's Syndrome$1$. It is an autosomal chromosomal disorder.$1$. It is a sex chromosomal disorder.$2$. It is caused by the

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(N/A) Down's SyndromeKlinefelter's Syndrome$1$. It is an autosomal chromosomal disorder.$1$. It is a sex chromosomal disorder.$2$. It is caused by the presence of an additional copy of chromosome number $21$.$2$. It is caused by the presence of an additional copy of $X$-chromosome.$3$. The karyotype is $47, XX, +21$ or $47, XY, +21$.$3$. The karyotype is $47, XXY$.$4$. It can occur in both males and females.$4$. It occurs only in males.

Class 12 Biology Principles of Inheritance and Variation Chromosomal disorders

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Distinguish between: Down's syndrome and Klinefelter's syndrome.

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Down's Syndrome	Klinefelter's Syndrome
$1$. It is an autosomal chromosomal disorder.	$1$. It is a sex chromosomal disorder.
$2$. It is caused by the presence of an additional copy of chromosome number $21$.	$2$. It is caused by the presence of an additional copy of $X$-chromosome.
$3$. The karyotype is $47, XX, +21$ or $47, XY, +21$.	$3$. The karyotype is $47, XXY$.
$4$. It can occur in both males and females.	$4$. It occurs only in males.