Which of the following structures are present | vedclass

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(A) nucleosome consists of a core particle and linker $DNA$. The core particle of a nucleosome is composed of an octamer of histone proteins ($H2A, H2

Vedclass · Accepted Answer

Octamer of histone proteins

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(A) nucleosome consists of a core particle and linker $DNA$. The core particle of a nucleosome is composed of an octamer of histone proteins ($H2A, H2B, H3, H4$ - two of each) around which approximately $146$ bp of $DNA$ is wrapped. Option $A$ is correct because the histone octamer forms the central core of the nucleosome. Option $B$ is incorrect because a complete nucleosome (including linker $DNA$) contains about $200$ bp of $DNA$,not just the core particle. Option $C$ is incorrect as non-histone proteins are not part of the nucleosome core. Option $D$ is incorrect because linker $DNA$ connects adjacent nucleosomes and is not part of the core particle itself.

Which of the following structures are present in the core particle of a nucleosome?

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