The DNA-histone complex can be removed from c | vedclass

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Question

(A) The $DNA$ molecule is negatively charged due to the phosphate backbone,while histones are positively charged proteins rich in basic amino acids li

Vedclass · Accepted Answer

$6\ M\ NaCl + Mg(OH)_2$

Vedclass · Answer

(A) The $DNA$ molecule is negatively charged due to the phosphate backbone,while histones are positively charged proteins rich in basic amino acids like lysine and arginine. The interaction between $DNA$ and histones is primarily electrostatic. By increasing the ionic strength of the solution using a high concentration of salt (like $6\ M\ NaCl$),the electrostatic attraction between the negatively charged $DNA$ and positively charged histones is disrupted,causing the histones to dissociate from the $DNA$.

The $DNA$-histone complex can be removed from chromosomes by treatment with:

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