Which enzyme was targetted during the first c | vedclass

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The first clinical gene therapy was given in $1990$ to a four- year- old girl with adenosine deaminase ($ADA$ deficiency). This enzyme is crucial for

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Adenosine deaminase

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The first clinical gene therapy was given in $1990$ to a four- year- old girl with adenosine deaminase ($ADA$ deficiency). This enzyme is crucial for the immune system to function because in its absence lymphocytes proliferation is inhibited. Without $T$ cells, $ADA-$deficient children are wide open to the attacks of viruses and bacteria.

Which enzyme was targetted during the first clinical gene therapy given in $1990$ to a four year- old girl?

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