(N/A) The juxtaglomerular apparatus $(JGA)$ is a complex regulatory structure formed by the contact point between the afferent arteriole and the distal convoluted tubule $(DCT)$ of the nephron.
The $JGA$ contains specialized cells in the afferent arteriole known as juxtaglomerular cells. These cells act as baroreceptors that sense changes in blood pressure or glomerular blood flow.
When there is a decrease in glomerular blood flow,glomerular blood pressure,or glomerular filtration rate $(GFR)$,the juxtaglomerular cells are activated to release the enzyme renin.
Renin converts the plasma protein angiotensinogen into angiotensin $I$,which is further converted into angiotensin $II$ by an angiotensin-converting enzyme.
Angiotensin $II$ acts as a powerful vasoconstrictor,which narrows the blood vessels,thereby increasing glomerular blood pressure and $GFR$.
Additionally,angiotensin $II$ stimulates the adrenal cortex to release aldosterone. Aldosterone promotes the reabsorption of sodium ions and water from the distal convoluted tubule and the collecting duct,which increases blood volume and blood pressure,thereby restoring $GFR$ to normal levels. This entire regulatory process is known as the renin-angiotensin-aldosterone system $(RAAS)$.