What is a recombinant $\rm {DNA}$ vaccine ? Give two examples.
A recombinant vaccine is a vaccine produced through recombinant $DNA$ technology. This involves inserting the $DNA$ encoding an antigen that stimulates an immune response into bacterial or mammalian cells. Recombinant $DNA$ technology has allowed the production of antigenic polypeptides of pathogen in bacteria or yeast. Vaccines produced using this approach allow large scale production and hence greater availability for immunisation, e.g., hepatitis $\mathrm{B}$ vaccine (Recombivax $HB$) produced from yeast. As of June $2015$, one human $DNA$ vaccine had been approved for human use, the single-dose Japanese encephalitis vaccine called $IMOJEV$, released in $2010$ in Australia.
Consider the following statements
$I$. Flavr savr is a genetically modified tomato, which remains fresh and retains its flavour much longer than the normal tomato due to blocking of synthesis of fruit softening enzyme polygalacturonase
$II$. Recently, the $US$ Government has patented the Indian 'basmati' rice as Rice-tec
$III$. Viruses, bacteria and some other harmful organisms can be used as bioweapons in biological warfare
Which of the statements given above are correct?
Grafting between two members of same species is
When and where first time word “biotechno logy'' was used
Who coined the term $ ”antibiotics''$