In sickle cell anaemia,the death is caused wh | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(C) Sickle cell anaemia is an autosomal recessive genetic disorder caused by a mutation in the $Hb^S$ gene.In the heterozygous condition $(Hb^A Hb^S)$

Vedclass · Accepted Answer

Homozygous recessive condition

Vedclass · Answer

(C) Sickle cell anaemia is an autosomal recessive genetic disorder caused by a mutation in the $Hb^S$ gene.In the heterozygous condition $(Hb^A Hb^S)$,the individual is a carrier and exhibits the sickle cell trait,which provides some resistance to malaria.In the homozygous recessive condition $(Hb^S Hb^S)$,the individual suffers from severe sickle cell anaemia.This condition leads to the production of abnormal haemoglobin,causing red blood cells to become sickle-shaped,which results in severe anaemia and often leads to premature death due to organ failure and complications. Thus,the lethal effect is observed in the homozygous recessive state.

In sickle cell anaemia,the death is caused when the lethal genes are present in

Similar Questions

$A$ marriage between a normal-visioned man and a colourblind woman will produce which of the following types of offspring?

Which genotype is responsible for the carrier state of sickle-cell anemia?

Given below is a pedigree chart showing the inheritance of a certain trait in humans. Select the correct option for the given chart.

Which of the following is a Mendelian disorder?

Both male and female have normal vision though their fathers were colour blind,and mothers did not have any gene for colour blindness. The probability of their daughter becoming colour blind is (in $\%$)

Vedclass Test Series

Exam Paper Generator

Online Exam Module