If ${ }^{n-3} C_r + B \cdot { }^{n-3} C_{r-1} + B^{\prime} \cdot { }^{n-3} C_{r-2} + { }^{n-3} C_{r-3} = { }^n C_r$ holds for all $n \geq r \geq 3$,then $(B, B^{\prime}) = $.

The domain of definition of the function $f(x) = \log_{[x + \frac{1}{x}]} |x^2 - x - 6| + ^{16-x}C_{2x-1} + ^{20-3x}P_{2x-5}$ is,where $[x]$ denotes the greatest integer function.

If $n$ objects are arranged in a row,then the number of ways of selecting three of these objects such that no two of them are next to each other is:

In how many ways can $5$ letters be selected from the letters of the word $INDEPENDENT$?

What is the number of ways of choosing $4$ cards from a pack of $52$ playing cards? In how many of these are two red cards and two black cards?

There are $6$ different novels and $3$ different poetry books on a table. If $4$ novels and $1$ poetry book are to be selected and arranged in a row on a shelf such that the poetry book is always in the middle,then the number of such possible arrangements is