(N/A) The respiratory rhythm centre present in the medulla region of the brain is primarily responsible for the regulation of respiration.
The pneumotaxic centre present in the pons region of the brain can moderate the functions of the respiratory rhythm centre by signaling to reduce the duration of inspiration,thereby altering the respiratory rate.
$A$ chemosensitive area situated adjacent to the rhythm centre is highly sensitive to $CO_2$ and hydrogen ions. An increase in these substances activates this centre,which in turn signals the rhythm centre to make necessary adjustments for the elimination of these substances.
Receptors associated with the aortic arch and carotid artery also recognize changes in $CO_2$ and hydrogen ion concentrations and send necessary signals to the respiratory rhythm centre for remedial actions.