How does pepsinogen get converted into its ac | vedclass

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(B) The proenzyme pepsinogen is secreted by the chief cells of the stomach.When pepsinogen comes in contact with hydrochloric acid $(HCl)$ secreted by

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By the action of hydrochloric acid $(HCl)$

Vedclass · Answer

(B) The proenzyme pepsinogen is secreted by the chief cells of the stomach.When pepsinogen comes in contact with hydrochloric acid $(HCl)$ secreted by the parietal cells,it undergoes a conformational change.This process converts the inactive proenzyme pepsinogen into the active proteolytic enzyme pepsin.This active pepsin then helps in the digestion of proteins into proteoses and peptones.

How does pepsinogen get converted into its active form?

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