(N/A) Neural regulation: Human beings have a significant ability to maintain and moderate the respiratory rhythm to suit the demands of the body tissues.
$A$ specialised centre present in the medulla region of the brain,called the respiratory rhythm centre,is primarily responsible for this regulation.
Another centre present in the pons region of the brain,called the pneumotaxic centre,can moderate the functions of the respiratory rhythm centre. Neural signals from this centre can reduce the duration of inspiration and thereby alter the respiratory rate.
$A$ chemosensitive area is situated adjacent to the rhythm centre,which is highly sensitive to $CO_2$ and hydrogen ions. An increase in these substances can activate this centre,which in turn can signal the rhythm centre to make necessary adjustments in the respiratory process by which these substances can be eliminated.