(N/A) According to collision theory,for a chemical reaction to occur,the reactant molecules must collide with sufficient kinetic energy (activation energy) and in the proper orientation.
The proper orientation of colliding molecules facilitates the breaking of bonds between reacting species and the formation of new bonds to yield products.
For example,the reaction between bromomethane $(CH_3Br)$ and the hydroxide ion $(OH^-)$ to form methanol $(CH_3OH)$ depends on the orientation of the reactant molecules. If the $OH^-$ ion approaches the carbon atom from the side opposite to the bromine atom,it results in the formation of products. If it approaches from the same side,no reaction occurs due to steric hindrance and electrostatic repulsion.