| Prokaryotic Cell | Eukaryotic Cell |
| $1$. Size is generally small $(0.5-10 \mu m)$. | $1$. Size is generally larger $(1-100 \mu m)$. |
| $2$. Nuclear region is not surrounded by a nuclear membrane. | $2$. Nuclear region is surrounded by a nuclear membrane. |
| $3$. Membrane-bound organelles such as mitochondria,lysosomes,and endoplasmic reticulum are absent. | $3$. All membrane-bound organelles are present. |
| $4$. Nucleolus is absent. | $4$. Nucleolus is present. |
| $5$. Cell division occurs by fission or budding (no mitosis). | $5$. Cell division is mitotic or meiotic. |
| $6$. They always have a single chromosome. | $6$. They have more than one chromosome. |
| $7$. $DNA$ is circular and lies free in the cytoplasm (no true nucleus). | $7$. $DNA$ is linear and contained within a nucleus. |
| $8$. $DNA$ is naked (not associated with histones). e.g.,$PPLO$,bacteria,and blue-green algae. | $8$. $DNA$ is associated with proteins (histones) to form chromosomes. e.g.,Plants and animals. |
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