Determine the correct configuration of the fo | vedclass

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(A) To determine the configuration,we assign priorities to the groups attached to each chiral center using the Cahn-Ingold-Prelog $(CIP)$ rules.For ca

Vedclass · Accepted Answer

$2S, 3S$

Vedclass · Answer

(A) To determine the configuration,we assign priorities to the groups attached to each chiral center using the Cahn-Ingold-Prelog $(CIP)$ rules.For carbon $2$:Priorities are: $1: -OH$,$2: -CH(OH)CH_3$,$3: -CH_3$,$4: -H$.Since the lowest priority group $(-H)$ is on a horizontal bond,the configuration is reversed. The sequence $1$ $\rightarrow 2$ $\rightarrow 3$ is clockwise $(R)$,so the actual configuration is $2S$.For carbon $3$:Priorities are: $1: -OH$,$2: -CH(OH)CH_3$,$3: -CH_3$,$4: -H$.Since the lowest priority group $(-H)$ is on a vertical bond,the configuration is not reversed. The sequence $1$ $\rightarrow 2$ $\rightarrow 3$ is counter-clockwise $(S)$,so the configuration is $3S$.Thus,the configuration is $2S, 3S$.

Determine the correct configuration of the following molecule:

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