Can a disease be detected before its symptoms appear? Explain the principle involved.
(N/A) Yes,a disease can be detected before its symptoms appear.
Normally,the presence of a pathogen (bacteria,viruses,etc.) is suspected only when it has produced disease symptoms. By this time,the concentration of the pathogen is already very high in the body.
However,a very low concentration of a bacteria or virus can be detected even when symptoms are not yet visible.
The principle involved is the amplification of their nucleic acid ($DNA$ or $RNA$) using $PCR$ (Polymerase Chain Reaction).
$PCR$ creates millions of copies of the specific $DNA$ sequence of the pathogen,making it detectable even if the initial sample contains only a few copies.
Normally,the presence of a pathogen (bacteria,viruses,etc.) is suspected only when it has produced disease symptoms. By this time,the concentration of the pathogen is already very high in the body.
However,a very low concentration of a bacteria or virus can be detected even when symptoms are not yet visible.
The principle involved is the amplification of their nucleic acid ($DNA$ or $RNA$) using $PCR$ (Polymerase Chain Reaction).
$PCR$ creates millions of copies of the specific $DNA$ sequence of the pathogen,making it detectable even if the initial sample contains only a few copies.
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Similar Questions
Given below are two statements.
Statement $I$ - The isolated $DNA$ of donor organism is cleaved by suitable restriction endonuclease to form $DNA$ fragments with cohesive staggered or blunt ends.
Statement $II$ - The foreign $DNA$ or passenger $DNA$ can also be obtained directly from genomic or cDNA library.
In the light of above statements,select the correct option given below:
Statement $I$ - The isolated $DNA$ of donor organism is cleaved by suitable restriction endonuclease to form $DNA$ fragments with cohesive staggered or blunt ends.
Statement $II$ - The foreign $DNA$ or passenger $DNA$ can also be obtained directly from genomic or cDNA library.
In the light of above statements,select the correct option given below:
How can a recombinant protein be obtained?
Medium
View SolutionIf $r-DNA$ containing the $amp^R$ gene is transferred into $E. coli$ cells,what will the normal $E. coli$ cells be transformed into?
Medium
View SolutionIn a mixture,$DNA$ fragments are separated by
Choose the correct statement:
$P -$ Endonucleases cut the $DNA$ at a specific site inside the $DNA$.
$Q -$ $A$ stirred-tank reactor is usually square in shape.
$R -$ In order to force bacteria to take up the plasmid,the bacterial cells must first be made 'competent' to take up $DNA$ by treating them with a divalent cation like $Ca^{2+}$.
$P -$ Endonucleases cut the $DNA$ at a specific site inside the $DNA$.
$Q -$ $A$ stirred-tank reactor is usually square in shape.
$R -$ In order to force bacteria to take up the plasmid,the bacterial cells must first be made 'competent' to take up $DNA$ by treating them with a divalent cation like $Ca^{2+}$.
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