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(B) Sickle-cell anemia is caused by a point mutation in the $\beta$-globin chain of hemoglobin,where glutamic acid is replaced by valine at the $6^{th

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Different mobility

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(B) Sickle-cell anemia is caused by a point mutation in the $\beta$-globin chain of hemoglobin,where glutamic acid is replaced by valine at the $6^{th}$ position. This substitution changes the electrical charge of the hemoglobin molecule. Because electrophoresis separates molecules based on their charge-to-mass ratio,normal hemoglobin $(HbA)$ and sickle-cell hemoglobin $(HbS)$ exhibit different electrophoretic mobilities. Therefore,they will show different mobility in an electrophoretic field.

Column-$I$	Column-$II$
$(1)$ Inheritance of two genes	$(a)$ $ABO$ blood group
$(2)$ Incomplete dominance	$(b)$ $1:2:1$
$(3)$ Codominance	$(c)$ $9:3:3:1$
$(4)$ Inheritance of one gene	$(d)$ $3:1$

When the blood hemoglobin of a normal person and a sickle-cell patient is placed in an electrophoretic field,what will be observed?

Similar Questions

Meiosis in $AaBb$ will produce gametes:

Match the following:

Column-$I$ Column-$II$

$(1)$ Inheritance of two genes $(a)$ $ABO$ blood group

$(2)$ Incomplete dominance $(b)$ $1:2:1$

$(3)$ Codominance $(c)$ $9:3:3:1$

$(4)$ Inheritance of one gene $(d)$ $3:1$

In maize, albinism is caused by the effect of:

Which of the following is $NOT$ an example of incomplete sex-linkage (pseudo-autosomal inheritance)?

$ABO$ blood type in man is an example of
$A$. Pleiotropy
$B$. Incomplete dominance
$C$. Co-dominance
$D$. Multiple allelism
Select the code for the correct answer from the options given below.

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