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(A) Base analogues are chemical compounds that structurally resemble the nitrogenous bases of $DNA$ (purines and pyrimidines). Because of their struct

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Base analogues

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(A) Base analogues are chemical compounds that structurally resemble the nitrogenous bases of $DNA$ (purines and pyrimidines). Because of their structural similarity,they can be incorporated into the $DNA$ molecule during replication in place of normal bases. Once incorporated,they often undergo tautomeric shifts,leading to incorrect base pairing during subsequent rounds of replication,which results in spontaneous mutations.

Column - $I$	Column - $II$
$(a)$ Helicase	$(1)$ Joining of nucleotides
$(b)$ Gyrase	$(2)$ Opening of $DNA$
$(c)$ Primase	$(3)$ Unwinding of $DNA$
$(d)$ $DNA$ Polymerase $III$	$(4)$ $RNA$ Priming

Mutagens that are effective in inducing spontaneous $DNA$ mutations are .....

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Match the columns.
Column - $I$ Column - $II$
$(a)$ Helicase $(1)$ Joining of nucleotides
$(b)$ Gyrase $(2)$ Opening of $DNA$
$(c)$ Primase $(3)$ Unwinding of $DNA$
$(d)$ $DNA$ Polymerase $III$ $(4)$ $RNA$ Priming

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