(C) In $1983$,the American company $Eli$ $Lilly$ produced two $DNA$ sequences corresponding to $A$ and $B$ chains of human insulin and introduced them

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(C) In $1983$,the American company $Eli$ $Lilly$ produced two $DNA$ sequences corresponding to $A$ and $B$ chains of human insulin and introduced them in plasmids of $Escherichia$ $coli$ to produce insulin chains. These chains were then extracted and combined by creating disulfide bonds to form human insulin.