Under what conditions does the inactive toxin | vedclass

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(D) The $Bt$ toxin produced by the bacterium $Bacillus 	ext{ thuringiensis}$ exists as an inactive protoxin in the bacteria. When an insect ingests t

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Alkaline $pH$

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(D) The $Bt$ toxin produced by the bacterium $Bacillus 	ext{ thuringiensis}$ exists as an inactive protoxin in the bacteria. When an insect ingests the inactive toxin, it enters the insect's gut. The gut of the insect provides an alkaline $pH$, which solubilizes the crystals and converts the inactive protoxin into its active form. This active toxin then binds to the surface of midgut epithelial cells and creates pores, causing cell swelling and lysis, eventually leading to the death of the insect.

Under what conditions does the inactive toxin of $Bt$ become active?

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