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(D) The transformation of $R$ cells into $S$ cells was demonstrated by Oswald Avery,Colin MacLeod,and Maclyn McCarty. They purified biochemicals (prot

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Deoxyribonucleic acid

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(D) The transformation of $R$ cells into $S$ cells was demonstrated by Oswald Avery,Colin MacLeod,and Maclyn McCarty. They purified biochemicals (proteins,$DNA$,$RNA$) from the heat-killed $S$ cells to see which one could transform live $R$ cells into $S$ cells. They discovered that $DNA$ alone from $S$ bacteria caused $R$ bacteria to become transformed. They also discovered that protein-digesting enzymes (proteases) and $RNA$-digesting enzymes (RNases) did not affect transformation,so the transforming substance was not a protein or $RNA$. Digestion with DNase did inhibit transformation,suggesting that the $DNA$ caused the transformation.

Which of the following was responsible for the transformation of $R$ cells into $S$ cells?

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