| Leading Strand | Lagging Strand |
| $(1)$ The leading strand is synthesized continuously in the $5' \rightarrow 3'$ direction. | $(1)$ The lagging strand is synthesized discontinuously in the $5' \rightarrow 3'$ direction. |
| $(2)$ No Okazaki fragments are formed. | $(2)$ Okazaki fragments are formed here. |
| $(3)$ $DNA$ polymerase adds new nucleotides towards the $3'$ end. Nucleotides are added one by one via phosphodiester bonds. | $(3)$ $DNA$ polymerase cannot add nucleotides in the direction of strand growth, hence continuous synthesis does not occur. |
| $(4)$ $A$ single $RNA$ primer is required at the start. | $(4)$ Multiple $RNA$ primers are required for each Okazaki fragment. |
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