Which one of the nitrogen atoms of histidine | vedclass

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Question

(B) In the imidazole ring of histidine,there are two nitrogen atoms: the pyrrole-like nitrogen $(\alpha-N)$ and the pyridine-like nitrogen $(\beta-N)$

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$ \beta $

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(B) In the imidazole ring of histidine,there are two nitrogen atoms: the pyrrole-like nitrogen $(\alpha-N)$ and the pyridine-like nitrogen $(\beta-N)$.The lone pair on the $\alpha-N$ is involved in the aromatic sextet of the imidazole ring.The lone pair on the $\beta-N$ is in an $sp^2$ orbital perpendicular to the aromatic ring and is available for protonation.Protonation at the $\beta-N$ leads to the formation of an imidazolium ion,which is stabilized by two equivalent resonance structures,making it the more basic site.

Type of Protein	Their Properties
$(A)$ Fibrous	$1$. Hydrogen bonding
$(B)$ Globular	$2$. Water soluble
	$3$. Spherical shape
	$4$. Disulphide linkage

Which one of the nitrogen atoms of histidine is protonated first?

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