Which one of the following vectors is used to replace the defective gene in gene therapy?

Match the following columns:

List-$I$	List-$II$
$(a)$ $1977$	$(1)$ Creation of the first transgenic cow
$(b)$ $1983$	$(2)$ American company obtained patent for Basmati rice
$(c)$ $1990$	$(3)$ Eli Lilly company prepared two $DNA$ sequences for insulin
$(d)$ $1997$	$(4)$ First clinical gene therapy trial

Which of the following vectors is used to transfer a functional $ADA$ $cDNA$ into the lymphocytes?

Human insulin is being commercially produced from a transgenic species of

Statement-$I$: In vitro fertilisation leading to a test tube baby is a part of biotechnology.
Statement-$II$: Developing a $\text{DNA}$ vaccine is a part of biotechnology.

Injecting functional adenosine deaminase into a patient's (lacking $ADA$ gene) blood cells may be considered as