Which of the following stages is affected by | vedclass

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(A) Colchicine is a chemical substance derived from the plant $Colchicum 	ext{ } autumnale$. It acts as a mitotic poison by binding to tubulin protei

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Metaphase

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(A) Colchicine is a chemical substance derived from the plant $Colchicum 	ext{ } autumnale$. It acts as a mitotic poison by binding to tubulin proteins, thereby inhibiting the polymerization of microtubules. Since microtubules are essential for the formation of spindle fibers during cell division, colchicine prevents the assembly of the spindle apparatus. This effect is specifically observed during $Metaphase$, as the chromosomes fail to align or separate properly due to the absence of spindle fibers.

Which of the following stages is affected by colchicine?

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