Which of the following reaction sequences sho | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(C) To achieve an overall inversion of configuration,the sequence must involve an odd number of $S_N2$ reactions.Option $A$: $R-Cl \xrightarrow{NaI/Ac

Vedclass · Accepted Answer

Vedclass · Answer

(C) To achieve an overall inversion of configuration,the sequence must involve an odd number of $S_N2$ reactions.Option $A$: $R-Cl \xrightarrow{NaI/Acetone} R-I$ (Inversion) $\xrightarrow{CH_3ONa/DMF} R-OCH_3$ (Inversion). Two inversions result in retention of configuration.Option $B$: $R-OH \xrightarrow{SOCl_2/Pyridine} R-Cl$ (Inversion) $\xrightarrow{CH_3ONa/DMF} R-OCH_3$ (Inversion). Two inversions result in retention of configuration.Option $C$: $R-OH \xrightarrow{SOCl_2} R-Cl$ (Retention via $S_Ni$ mechanism) $\xrightarrow{CH_3ONa/DMF} R-OCH_3$ (Inversion). One inversion results in overall inversion of configuration.Option $D$: $R-OH$ $\xrightarrow{Na} R-ONa$ $\xrightarrow{CH_3-I} R-OCH_3$. This is the Williamson ether synthesis,which proceeds with retention of configuration at the chiral center.

Which of the following reaction sequences shows an overall inversion of configuration in the product?

Similar Questions

The product $X$ is
[Image: $1-$chloro$-1-$($2$-chloroethyl)cyclopentane] $\xrightarrow{LiBr/DMSO, S_N2 \text{ conditions}}$ Major product $(X)$

Which of the following compounds has the highest reactivity towards $S_N2$ reaction?

Which of the following reagents is used in the preparation of nitroalkane from haloalkane?

Compare the relative rate of reaction with $H_2O$ for the following compounds:

Which of the following reactions is used for the conversion of alkyl chloride to alkyl iodide?

Vedclass Test Series

Exam Paper Generator

Online Exam Module