When a cell is treated with citrate and malon | vedclass

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(C) Malonate is a competitive inhibitor of the enzyme succinate dehydrogenase,which converts succinic acid to fumaric acid in the Krebs cycle. When a

Vedclass · Accepted Answer

Kreb's cycle is suppressed halfway and succinic acid accumulates

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(C) Malonate is a competitive inhibitor of the enzyme succinate dehydrogenase,which converts succinic acid to fumaric acid in the Krebs cycle. When a cell is treated with malonate,the conversion of succinic acid is blocked,leading to its accumulation. Citrate is an intermediate of the Krebs cycle,and its presence does not override the inhibition caused by malonate. Therefore,the cycle is suppressed at the stage of succinate dehydrogenase,causing succinic acid to accumulate.

When a cell is treated with citrate and malonate,what is the effect on the Krebs cycle?

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