What do prostaglandins influence?

What is the role of the second messenger in hormone action?

Which one of the following flows directly into blood from the seat of its production to act on an organ away from it?

Which of the following hormones never enters the cytoplasm of the target cell?

Given below are two statements.
Statement $I$: Mode of action of catecholamines,peptide and polypeptide hormones is through cell membrane receptors.
Statement $II$: These hormones are non-steroid,water soluble and lipid insoluble hormones.
In the light of above statements,choose the correct option from below:

Which of the following hormones uses $Ca^{++}$ as a second messenger?