What are the major causes of species losses in a geographical region?

(N/A) Biodiversity is the variety of living forms present in various ecosystems. It includes variability among life forms from all sources including land,air,and water. Biodiversity around the world is declining at a very fast pace. The following are the major causes for the loss of biodiversity around the world:
$1$. Habitat loss and fragmentation: Habitats of various organisms are altered or destroyed by uncontrolled and unsustainable human activities such as deforestation,slash-and-burn agriculture,mining,and urbanization. This results in the breaking up of the habitat into small pieces,which affects the movement of migratory animals and decreases the genetic exchange between populations,leading to a decline in species.
$2$. Over-exploitation: Due to over-hunting and over-exploitation of various plants and animals by humans,many species have become endangered or extinct (such as the tiger and the passenger pigeon).
$3$. Alien species invasions: Accidental or intentional introduction of non-native species into a habitat has also led to the decline or extinction of indigenous species. For example,the Nile perch introduced in Lake Victoria in Kenya led to the extinction of more than $200$ species of native fish in the lake.
$4$. Co-extinction: In a native habitat,one species is connected to the other in an intricate network. The extinction of one species causes the extinction of other species,which is associated with it in an obligatory way. For example,the extinction of the host will cause the extinction of its parasites.