The substitution of one purine $N_2$ base with another purine base or one pyrimidine $N_2$ base with another pyrimidine base is known as:

  • A
    Transition
  • B
    Transversion
  • C
    Translocation
  • D
    Transcription

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Assertion $(A):$ The split gene arrangement represents probably an ancient feature of the genome.
Reason $(R):$ $\text{hnRNA}$ undergoes additional processing called as capping and tailing.
Choose the correct option.

In sickle-cell anemia,what is the sequence of the defective nitrogen base on the $DNA$ strand that does not act as a template?

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Study the given figure of a nucleosome and select the option that correctly identifies the parts $A, B$ and $C$.

$A$: Teminism is the unidirectional flow of information.
$R$: It requires $DNA$-dependent $RNA$ polymerase enzyme.

Assertion : Histones are basic proteins of major importance in packaging of eukaryotic $DNA$. $DNA$ and histones comprise chromatin forming the bulk of eukaryotic chromosome.
Reason : Histones are of five major types $H_1, H_2A, H_2B, H_3$ and $H_4$.

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