The result of which of the following reaction | vedclass

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(A) The correct answer is $A$. Oswald Avery, Colin MacLeod, and Maclyn McCarty worked to determine the biochemical nature of the 'transforming princip

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Live '$R$' strain + $DNA$ from '$S$' strain + $RNAase$

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(A) The correct answer is $A$. Oswald Avery, Colin MacLeod, and Maclyn McCarty worked to determine the biochemical nature of the 'transforming principle' in Griffith's experiment. They purified biochemicals (proteins, $DNA$, $RNA$) from the heat-killed '$S$' cells to see which ones could transform live '$R$' cells into '$S$' cells. They discovered that digestion with $proteases$ and $RNAases$ did not affect transformation, meaning neither protein nor $RNA$ was the genetic material. However, digestion with $DNAase$ inhibited the transformation, proving that $DNA$ is the substance that causes the transformation of '$R$' strain into '$S$' strain. Therefore, the experiment that conclusively proved $DNA$ is the genetic material involved the addition of $DNAase$ to the mixture, which prevented the transformation.

The result of which of the following reaction experiments carried out by Avery et al. on $Streptococcus \text{ } pneumoniae$ has proved conclusively that $DNA$ is the genetic material?

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