The most popularly known blood grouping is the $ABO$ grouping. It is named $ABO$ and not $ABC$, because "$O$" in it refers to having

  • A
    overdominance of this type on the genes for $A$ and $B$ types
  • B
    one antibody only - either anti-$A$ or anti-$B$ on the $RBCs$
  • C
    no antigens $A$ and $B$ on $RBCs$
  • D
    other antigens besides $A$ and $B$ on $RBCs$

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