The dipeptide,Gln-Gly,on treatment with CH_3C | vedclass

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(D) The dipeptide $Gln-Gly$ consists of Glutamine $(Gln)$ at the $N$-terminus and Glycine $(Gly)$ at the $C$-terminus. The structure of $Gln-Gly$ is $

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(D) The dipeptide $Gln-Gly$ consists of Glutamine $(Gln)$ at the $N$-terminus and Glycine $(Gly)$ at the $C$-terminus. The structure of $Gln-Gly$ is $H_2N-CH(CH_2CH_2CONH_2)-CONH-CH_2-COOH$.When treated with $CH_3COCl$ (acetyl chloride),the primary amino group $(-NH_2)$ at the $N$-terminus is acetylated to form an acetamide group $(-NHCOCH_3)$.The amide group $(-CONH_2)$ present in the side chain of Glutamine is significantly less nucleophilic due to resonance stabilization and is generally not acetylated under these conditions.Therefore,the product is $CH_3CONH-CH(CH_2CH_2CONH_2)-CONH-CH_2-COOH$,which corresponds to the structure shown in option $D$.

The dipeptide,$Gln-Gly$,on treatment with $CH_3COCl$ followed by aqueous work-up gives:

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