Symptoms of paroxysms in malaria are due to

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(D) The symptoms of malaria,such as chills and high fever (paroxysms),are caused by the release of a toxic substance called $hemozoin$ into the blood.

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Erythrocytic cycle

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(D) The symptoms of malaria,such as chills and high fever (paroxysms),are caused by the release of a toxic substance called $hemozoin$ into the blood.This release occurs when the $Plasmodium$ parasite completes its $erythrocytic$ $cycle$ (the cycle within red blood cells) and ruptures the host's red blood cells.Therefore,the correct answer is the $erythrocytic$ $cycle$.

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