Select the correct statement with respect to disorders of muscles in humans.

  • A
    Failure of neuromuscular transmission in myasthenia gravis can prevent normal swallowing.
  • B
    Accumulation of urea and creatine in the joints causes their inflammation.
  • C
    An overdose of vitamin $D$ causes osteoporosis.
  • D
    Rapid contractions of skeletal muscles cause muscle dystrophy.

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Assertion: Inflammation of a skeletal joint may immobilize the movements of the joint.
Reason: Uric acid crystals in the joint cavity and ossification of articular cartilage lead to this.

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