Periodic appearance of malaria symptoms occur | vedclass

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(D) The periodic appearance of malaria symptoms,known as paroxysm,is caused by the release of a toxic substance called haemozoin into the blood.When t

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Release of pyrogen in blood

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(D) The periodic appearance of malaria symptoms,known as paroxysm,is caused by the release of a toxic substance called haemozoin into the blood.When the $Plasmodium$ parasite completes its erythrocytic cycle,the infected red blood cells rupture.This rupture releases merozoites along with the toxic haemozoin and other metabolic waste products into the bloodstream.The presence of these toxins triggers the immune system,leading to the characteristic chills and high fever associated with malaria.Therefore,the periodic release of these substances into the blood corresponds to the periodic nature of the symptoms.

Periodic appearance of malaria symptoms occurs due to periodic

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