| Column-$I$ | Column-$II$ |
|---|---|
| $(1)$ Lethal mutation | $(a)$ Mutation caused by external factors |
| $(2)$ Spontaneous mutation | $(b)$ They are metabolic errors |
| $(3)$ Induced mutation | $(c)$ As a result the mutant dies |
| $(4)$ Biochemical mutation | $(d)$ Most of the mutations occurring in nature are of this type |
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