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(B) The reaction of a nitrile $(R-CN)$ with a Grignard reagent $(R'MgX)$ followed by acid hydrolysis $(H_3O^+)$ is a standard method to synthesize ket

Vedclass · Accepted Answer

$m	ext{-Methylacetophenone}$

Vedclass · Answer

(B) The reaction of a nitrile $(R-CN)$ with a Grignard reagent $(R'MgX)$ followed by acid hydrolysis $(H_3O^+)$ is a standard method to synthesize ketones.$1$. The Grignard reagent $(CH_3MgBr)$ acts as a nucleophile and attacks the electrophilic carbon of the nitrile group $(-CN)$.$2$. This forms an imine intermediate: $m	ext{-CH}_3C_6H_4-C(CH_3)=NMgBr$.$3$. Subsequent acid hydrolysis $(H_3O^+)$ converts the imine intermediate into a ketone.$4$. The final product is $m	ext{-methylacetophenone}$ (also known as $3	ext{-methylacetophenone}$).Therefore,the correct option is $B$.

Predict the product of the following reaction:
$m\text{-Tolunitrile} \xrightarrow[(ii) H_3O^+]{(i) CH_3MgBr} \text{Product}$

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Predict the product of the following reaction:$m\text{-Tolunitrile} \xrightarrow[(ii) H_3O^+]{(i) CH_3MgBr} \text{Product}$