Increase in the excitability of nerves and mu | vedclass

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(D) The excitability of nerves and muscles is regulated by the concentration of ions,particularly $Ca^{2+}$.Parathyroid hormone $(PTH)$ is a hypercalc

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Hypoactivity of parathyroid

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(D) The excitability of nerves and muscles is regulated by the concentration of ions,particularly $Ca^{2+}$.Parathyroid hormone $(PTH)$ is a hypercalcemic hormone,meaning it increases blood $Ca^{2+}$ levels by stimulating bone resorption (osteoclast activity).$A$ decrease in $PTH$ activity (hypoactivity) leads to hypocalcemia,which is a low level of $Ca^{2+}$ in the blood.Low levels of $Ca^{2+}$ lower the threshold for nerve impulse generation,thereby increasing the excitability of nerves and muscles.This increased excitability results in sustained contractions or spasms of the muscles of the larynx,face,hands,and feet,a condition known as tetany.

Increase in the excitability of nerves and muscles leading to sustained contraction of the muscles of larynx,face,hand and feet is due to

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