In gene therapy of Adenosine Deaminase $(ADA)$ deficiency,the patient requires periodic infusion of genetically engineered lymphocytes because
- AGene isolated from marrow cells producing $ADA$ is introduced into cells at embryonic stages.
- BLymphocytes from patient's blood are grown in culture,outside the body.
- CGenetically engineered lymphocytes are not immortal cells.
- DRetroviral vector is introduced into these lymphocytes.
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View SolutionAt present,about $X$ recombinant therapeutics have been approved for human use the world over. Out of these,$Y$ are being marketed in India.
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View SolutionCorrect chronological order of the steps occurring during gene therapy are
$I$. Lymphocytes are obtained from the patients
$II$. Lymphocytes are transferred to the culture dishes
$III$. Lymphocytes are transfected with the normal $ADA$ genes
$IV$. The transfected cells are returned to the patients
The chronological order should be
$I$. Lymphocytes are obtained from the patients
$II$. Lymphocytes are transferred to the culture dishes
$III$. Lymphocytes are transfected with the normal $ADA$ genes
$IV$. The transfected cells are returned to the patients
The chronological order should be
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