Failure of insulin production results in

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(D) Insulin is a peptide hormone secreted by the $\beta$-cells of the Islets of Langerhans in the pancreas.It plays a major role in the regulation of

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Diabetes mellitus

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(D) Insulin is a peptide hormone secreted by the $\beta$-cells of the Islets of Langerhans in the pancreas.It plays a major role in the regulation of glucose homeostasis by enhancing cellular glucose uptake and utilization.Failure of insulin production or secretion leads to a condition known as Diabetes mellitus,characterized by prolonged hyperglycemia (high blood glucose levels) and the excretion of glucose in the urine (glycosuria).

Column-$I$	Column-$II$
$A$. Alpha cells	$I$. Stimulates muscles for glycogenesis.
$B$. Beta cells	$II$. Decreases gastric secretions and absorption in digestive tract.
$C$. Delta cells	$III$. Inhibits the release of pancreatic juice.
$D$. $F$ cells	$IV$. Stimulates liver for glycogenolysis.

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