| Rough Endoplasmic Reticulum $(RER)$ | Smooth Endoplasmic Reticulum $(SER)$ |
|---|---|
| $(i)$ Ribosomes are present on its surface,giving it a rough appearance. | $(i)$ Ribosomes are absent on its surface,giving it a smooth appearance. |
| $(ii)$ It is primarily involved in protein synthesis and modification. | $(ii)$ It is primarily involved in the synthesis of lipids,steroids,and glycogen metabolism. |
| $(iii)$ It is abundant in cells actively synthesizing proteins,such as liver cells or pancreatic cells. | $(iii)$ It is abundant in cells synthesizing steroids and lipids,such as cells of the testis,ovary,and adrenal cortex. |
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