Cirrhosis of the liver is caused by the chronic intake of

From which plant is cocaine obtained?

$S$ - Statement: Adolescence is the period between $12$ and $18$ years of age.
$R$ - Reason: Curiosity for excitement and adventure is necessary during adolescence.

Given below are two statements with respect to the neurotransmitter,$Dopamine$.
Statement-$I$: Degeneration of $Dopamine$-producing neurons causes $Parkinson's$ disease.
Statement-$II$: $Dopamine$ level increases due to cocaine.
Choose the most appropriate answer from the options given below.

For Assertion $A$ and Reason $R$:
Assertion $A$: Smoking increases blood pressure and heart rate.
Reason $R$: Nicotine stimulates the adrenal gland.

$Heroin$ : slows down body functions :: $cocaine$ :