Choose the correct option.

$A$. Growth hormone	$i$. Osteoporosis
$B$. Thyroxin	$ii$. Diabetes mellitus
$C$. Parathormone	$iii$. Cretinism
$D$. Insulin	$iv$. Acromegaly

Given below is an incomplete table on hormones,their source glands,and one major effect on the human body. Identify the option representing the correct grouping of hormone,its gland,and effect.

Gland	Secretion	Effect on body
$A$	Estrogen	Maintenance of secondary sexual characters
Alpha cells of Islets of Langerhans	$B$	Raises blood sugar level
Anterior pituitary	$C$	Over secretion leads to gigantism

Type $II$ $(NIDDM)$ hyperglycemia is caused due to . . . . . .
$(a)$ Failure of insulin to facilitate the movement of glucose into cells.
$(b)$ Reduced sensitivity to insulin.
$(c)$ Under-activity of beta cells resulting in increased secretion of insulin.
$(d)$ Reduced reabsorption of water and increased urine output.
Select the correct option given below.

Which of the following organ systems jointly coordinate and integrate all the activities of the body organs?

Both adrenaline and cortisol are secreted in response to stress. Which of the following statements is true for both of these hormones?

Given below are two statements. Read them and choose the correct pair below.
Statement-$I$: Melatonin regulates the sleep-wake cycle,body temperature,metabolism,and reproductive cycles.
Statement-$II$: Thyroxin increases the action of neurotransmitters and supports the $RBC$ production.